oligoclonal bands


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Related to oligoclonal bands: albuminocytologic dissociation

oligoclonal bands

Immunoglobulins found in the cerebrospinal fluid of patients with multiple sclerosis (MS) and, occasionally, in other neurological conditions. They are used as a marker of MS when magnetic resonance imaging studies of the brain are not diagnostic.
See also: band
References in periodicals archive ?
Early differential diagnosis of multiple sclerosis using a new oligoclonal band test," Archives of Neurology, vol.
M-B: Cerebrospinal fluid Chemistry and Oligoclonal Bands.
2 CSF oligoclonal bands Present CSF: cerebrospinal fluid; igG: immunoglobulin G; RBC: red blood cell * Results were negative for gonorrhea, chlamydia, lupus, human immunodeficiency virus, syphilis, Lyme disease, varicella zoster virus, West Nile virus, herpes simplex virus, Epstein-Barr virus, cytomegalovirus, tuberculosis, and California, St.
Special proteins called oligoclonal bands are found in the spinal fluid of 80% of people with MS.
Lumbar puncture was performed and showed normal cerebral-spinal fluid (CSF) in the routine tests, including the cell count and protein concentration, as well as negative oligoclonal bands.
In summary cerebral white matter lesions may be observed in IBD and presence of pattern 3 oligoclonal bands in the CSF may suggest a comorbid MS or an extra-intestinal manifestation of IBD Clustering of autoimmune diseases and cancers in certain families may be incidental or triggered by certain common genes or environmental factors or a combination of both.
Oligoclonal bands were however absent in CSF although the CSF Proteins were elevated.
Similarly, lipid microarrays detected substantial reactivity of oligoclonal bands with myelin lipids (70), an important observation because lipid-reactive oligoclonal bands have been linked to disease progression in MS (71).
CSF analysis disclosed elevated protein with positive oligoclonal bands and myelin basic protein.
Polyclonal gammopathy and oligoclonal bands were significantly increased in HIV-positive patients.
To show that the oligoclonal bands are IgG-specific, the IEF should be followed by immuno-fixation with IgG-specific antibodies.