Early differential diagnosis of multiple sclerosis using a new oligoclonal band
test," Archives of Neurology, vol.
M-B: Cerebrospinal fluid Chemistry and Oligoclonal Bands
2 CSF oligoclonal bands
Present CSF: cerebrospinal fluid; igG: immunoglobulin G; RBC: red blood cell * Results were negative for gonorrhea, chlamydia, lupus, human immunodeficiency virus, syphilis, Lyme disease, varicella zoster virus, West Nile virus, herpes simplex virus, Epstein-Barr virus, cytomegalovirus, tuberculosis, and California, St.
Special proteins called oligoclonal bands
are found in the spinal fluid of 80% of people with MS.
Lumbar puncture was performed and showed normal cerebral-spinal fluid (CSF) in the routine tests, including the cell count and protein concentration, as well as negative oligoclonal bands
In summary cerebral white matter lesions may be observed in IBD and presence of pattern 3 oligoclonal bands
in the CSF may suggest a comorbid MS or an extra-intestinal manifestation of IBD Clustering of autoimmune diseases and cancers in certain families may be incidental or triggered by certain common genes or environmental factors or a combination of both.
were however absent in CSF although the CSF Proteins were elevated.
Similarly, lipid microarrays detected substantial reactivity of oligoclonal bands
with myelin lipids (70), an important observation because lipid-reactive oligoclonal bands
have been linked to disease progression in MS (71).
No oligoclonal bands
were observed in the CSF and the IgG index was normal (0,61).
CSF analysis disclosed elevated protein with positive oligoclonal bands
and myelin basic protein.
Polyclonal gammopathy and oligoclonal bands
were significantly increased in HIV-positive patients.
To show that the oligoclonal bands
are IgG-specific, the IEF should be followed by immuno-fixation with IgG-specific antibodies.