The yeast oestrogen screen, previously described by Routledge and Sumpter, 1996  was used to assess the oestrogenic
potency of the naturally occurring 17p-oestradiol and Bisphenol A.
Measurement of vitellogenin, a biomarker for exposure to oestrogenic
chemicals, in a wide variety of cyprinid fish.
11) In our study we found that prophylactic use of LNG-IUS before the start of tamoxifen treatment effectively reduced its oestrogenic
effect on the endometrium.
The tests included both multi-use and disposable PET bottles, and found that the multi-use PET bottles caused a behaviour more akin to that of the glass bottles--water in the glass and returnable PET bottles was non-oestrogenic
while that in the single use bottle was oestrogenic
effect of phytooestrogens produces reproductive disturbances in sheep, and a phytooestrogenrich diet is associated with a lower risk of breast and prostate cancer, and of cardiovascular disease (Adlercreutz, 1990).
The effect of p-nonylphenol, an environmental toxicant with oestrogenic
properties, on fertility potential in adult male rats.
It appears to have an oestrogenic
effect on the body, making it ideal for premenstrual and menopausal symptoms.
Studies in human cell lines indicated that the two oils had oestrogenic
and antiandrogenic activities.
administered substances with a "thyrostatic, oestrogenic
Carried out by Dr Jayne Brian and Professor John Sumpter at Brunei University's Institute for the Environment, the research highlights that a combination of oestrogenic
chemicals are negatively impacting the fertility, reproduction and gender of aquatic life and could also affect reproductive parameters in humans.
Dr Philippa Darbre, who works in the School of Biological Sciences, at the University of Reading, and who wrote the review, said, 'Since oestrogen is known to be involved in the development and progression of human breast cancer, any components of the environment that have oestrogenic
activity and which can enter the human breast could, theoretically, influence a woman's risk of breast cancer.
In vitro studies indicate that isoflavonoids have significant oestrogenic
activity, providing a supporting mechanism.