oestrogen receptor negative

oestrogen receptor negative

adjective Referring to breast cancer cells that lack a receptor to which estrogens can attach; ERN cancers usually have a worse prognosis, as they tend not to respond to anti-oestrogen therapy.
References in periodicals archive ?
Comparison of lipid profile between premenopausal test group and control group showed no difference of statistical significance as premenopausal patients were oestrogen receptor negative.
This work tells us that cancers which become refractory to anti-oestrogen treatment often do so by elevating their levels of ELF5 and becoming functionally oestrogen receptor negative," said Ormandy.
38, comparing t allele carriers with noncarriers) but not for oestrogen receptor negative tumours (OR = 0.
Efficacy has not been demonstrated in patients with oestrogen receptor negative status.
Here the lymph node size and the oestrogen receptor status is compared; in most of the cases the lymph node numbers were between 4 and 10 and they were mostly oestrogen receptor negative.
Here the grade of the tumour is compared with the oestrogen receptor status; in this study most of the cases were Grade 2 and they showed oestrogen receptor negative and the negativity is found to increase with increase in grade of the tumour.
We also see that although mammographic density is one of the strongest risk factors for breast cancer it doesn't seem to influence tumour development in any specific way; for instance, it isn't more associated with oestrogen receptor positive tumours than oestrogen receptor negative tumours, but seems to act as a general stimulator of tumour development," she noted.