oestrogen


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es·tro·gen

(es'trō-jen),
Generic term for any substance, natural or synthetic, that exerts biologic effects characteristic of estrogenic hormones such as 17β-estradiol. Estrogens are formed by the ovary, placenta, testes, and possibly the adrenal cortex, as well as by certain plants; they stimulate secondary sexual characteristics, and exert systemic effects, such as growth and maturation of long bones, and are used therapeutically in any disorder attributable to estrogen deficiency or amenable to estrogen therapy, such as menstrual disorders and menopausal problems. They control the course of the menstrual cycle.
Synonym(s): estrin, oestrogen
[G. oistrus, -heat, estrus, + -gen, producing]

oestrogen

(ĕs′trə-jən)
n.
Variant of estrogen.

oestrogen

See estrogen.

oestrogen

The steroid molecule which is the primary female sex hormone. It diffuses across cell membranes, and, once inside the cell, binds and activates oestrogen receptors, leading to modulation of the expression of a range of genes.

Pronunciation
Medspeak-UK: pronounced, EE stroh jenn
Medspeak-US: pronounced, ESS troh jenn

es·tro·gen

(es'trŏ-jen)
Generic term for any substance, natural or synthetic, which exerts biologic effects characteristic of estrogenic hormones; formed by the ovary, placenta, testes, and possibly the cortex of the suprarenal gland, as well as by some plants; stimulates secondary sexual characteristics and exerts systemic effects, such as growth and maturation of long bones; until recently, given after menopause or oophorectomy to prevent heart attack and prevent osteoporosis; also used to prevent or stop lactation, suppress ovulation, and palliate carcinoma of the breast and prostate.
Synonym(s): oestrogen.
[G. oistrus, -heat, estrus, + -gen, producing]

oestrogen

One of a group of steroid sex hormones secreted mainly by the ovaries, but also by the testicles. Oestrogens bring about the development of the female secondary sexual characteristics and act on the lining of the uterus, in conjunction with progesterone, to prepare it for implantation of the fertilized OVUM. They have some ANABOLIC properties and promote bone growth. Oestrogens are used to treat ovarian insufficiency and menopausal symptoms, to limit postmenopausal OSTEOPOROSIS, to stop milk production (lactation) and to treat widespread cancers of the PROSTATE gland. They are extensively used as oral contraceptives. Brand names are Premarin and, with Norgestrel, Prempac-C.

oestrogen

or

estrogen

a hormone produced by the OVARY of the female vertebrate which maintains the female SECONDARY SEXUAL CHARACTERS and is involved in the repair of the uterine wall after menstruation (see MENSTRUAL CYCLE). It is also produced by the PLACENTA during pregnancy, and in small quantities by the ADRENAL CORTEX and the male TESTIS.

oestrogen

natural or synthetic substances that induce development of secondary sexual characteristics, growth and maturation of long bones during youth; used therapeutically to treat carcinoma of breast and prostate

es·tro·gen

(es'trŏ-jen)
Generic term for any substance, natural or synthetic, which exerts biologic effects characteristic of estrogenic hormones; formed by the ovary, placenta, testes, and possibly the cortex of the suprarenal gland, as well as by some plants; stimulates secondary sexual characteristics and exerts systemic effects, such as growth and maturation of long bones; also used to prevent or stop lactation, suppress ovulation, and palliate carcinoma of the breast and prostate.
Synonym(s): oestrogen.
[G. oistrus, -heat, estrus, + -gen, producing]

oestrogen

References in periodicals archive ?
In order to develop an oestrogen treatment that utilises the favourable effects of the oestrogen but not its side-effects, researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have analysed which parts of the oestrogen receptor is most important in enabling oestrogen to act on bone tissue and other tissues.
Previously, inactivation of the oestrogen receptor has been shown to be mainly via DNA methylation or histone acetylation and in this type of oestrogen receptor-negative environment the only way of re-expressing the oestrogen receptor has been via DNA methylation inhibitors or histone deacetylation compounds.
Several environmental oestrogens are also anti-androgens.