odontogenic keratocyst


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o·don·to·gen·ic ke·ra·to·cyst

a cyst of dental lamina origin with a high recurrence rate and well-defined histologic criteria of a corrugated parakeratin surface, uniformly thin epithelium, and a palisaded basal layer. One manifestation of the basal cell nevus syndrome.

odontogenic keratocyst

a distinctive developmental odontogenic cyst which arises from the dental lamina, containing clear fluid and a cheesy material resembling keratin debris. This usually asymptomatic lesion can occur at any age and is found upon radiographic or dental imaging. Large lesions may present with pain, swelling, or drainage.

keratocystic odontogenic tumour

A benign cystic lesion of the jaw—75% in mandible, 90% behind canines—which arises in the dental lamina, often associated with impacted teeth; average age, 41 years; male:female ratio, 2:1. If multiple tumours are seen, basal cell nevus syndrome (a condition accompanied by basal cell carcinoma, ovarian fibroma, palmar pits, and medulloblastoma) should be excluded.

Management
KCOTs notoriously recur; initial surgery should include a generous margin and a rim of uninvolved bone.

o·don·to·gen·ic ker·a·to·cyst

(ō-don'tō-jen'ik ker'ă-tō-sist)
A cyst originating in the dental lamina that has a high recurrence rate, a corrugated parakeratin surface, uniformly thin epithelium, and a palisaded basal layer; one manifestation of the basal cell nevus syndrome.

o·don·to·gen·ic ker·a·to·cyst

(ō-don'tō-jen'ik ker'ă-tō-sist)
Lesion of dental lamina origin with a high recurrence rate and well-defined histologic criteria of corrugated parakeratin surface, uniformly thin epithelium, and a palisaded basal layer. One manifestation of the basal cell nevus syndrome.

odontogenic keratocyst (OKC),

References in periodicals archive ?
Histopathological examination of the excised specimens revealed features of odontogenic keratocyst.
Gorlin syndrome (also known as Gorlin-Goltz syndrome) is a condition characterised by multiple odontogenic keratocysts, basal cell carcinoma, congenital skeletal abnormalities, cleft lip and/or palate, and eye anomalies.
Hence ICAM-1 & VCAM-1 play an important role in the pathogenesis and development of periodontal diseases [23], odontogenic keratocyst & ameloblastoma [24], however, no study up to our knowledge had investigated the expression and role of ICAM-1 and VCAM-1 in other common oral lesions like pyogenic granuloma.
Expression of ICAM-1 & VCAM-1 in human ameloblastoma & odontogenic keratocyst, Shanghai Kou Qiang Yi Xue.
Marsupialization has been reported as a definitive treatment for extensive cysts, including the more aggressive and highly recurrent odontogenic keratocyst.
For the fourth edition, the title has been changed from the original Cysts of the Oral Region to better reflect the text's scope and the material has been updated in accord with the expanded literature of the field, particularly in reference to the odontogenic keratocyst.
Clinicopathological study of odontogenic keratocyst.
The differential diagnosis should include mucocele and odontogenic keratocyst.
Correlating imaging and histopathology of an odontogenic keratocyst in the nevoid basal cell carcinoma syndrome.
This is associated with basal cell nevus syndrome (Gorlin syndrome/nevoid basal cell syndrome) with symptoms such as numerous basal cell carcinomas, tumour formation, odontogenic keratocysts, and small abnormally shaped teeth and alveolar bone [Chuong et al.
Its initial description in 1960 by Gorlin and Goltz included the classic features of basal cell carcinoma, odontogenic keratocysts, and bifid ribs.
Lesions of this size can occur in odontogenic keratocysts, in ameloblastic fibromas, and in Pingborg's tumors, which originate from odontogenic sources.