Although unnecessary for diagnosis, there is a high Ki-67 and p53 expression in the neoplastic cells, ft is important to separate KCOTs from dentigerous cysts, orthokeratinized odontogenic cysts
, and periapical cysts, as these other entities do not have the same potential for recurrence or syndrome association.
Cytokeratin and p53 expression of odontogenic cysts
Ameloblastomas arise from residual epithelial elements of tooth development: dental lamina, enamel organ, lining of odontogenic cysts
or the basal cells of the oral mucosa.
Radicular cysts are odontogenic cysts
which are derived from the inflammatory activation of epithelial root sheath residues (cell rests of Malassez) [Main, 1985].
Anatomic Location of Orthokeratinized Odontogenic Cysts
(OOCs) and Comparison With Keratocystic Odontogenic Tumors (KCOTs) Reported Previously by Our Group Cases, Maxilla (%) Lesion No.
In the new WHO classification, published in 2005, PIOSCC is designated to replace the old terms, and its subtypes include solid types, PIOSCC derived from keratocystic odontogenic tumors, and those derived from odontogenic cysts
, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws.
Gorlin's syndrome with associated odontogenic cysts
The differential diagnosis includes other midline cysts, odontogenic cysts
, abscesses from anterior maxillary teeth, and furuncles or neoplasms of the nasal vestibule.
Metaplasia and degeneration in odontogenic cysts
Ameloblastoma can originate in the dental lamina (or its derivatives, such as epithelial rests), in the epithelial lining of odontogenic cysts
, in basal cells of the surface epithelium, and in epithelium of the enamel organ.
Dentigerous cysts are the most common type of developmental odontogenic cyst