Oculopharyngeal muscular dystrophy | definition of oculopharyngeal muscular dystrophy by Medical dictionary
oculopharyngeal muscular dystrophy
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oculopharyngeal muscular dystrophy Abbreviation: OPMD
A rare form of muscular dystrophy in which muscles that control the eyelids and swallowing are primarily affected. Ptosis and dysphagia beginning in the patient's late 40s or early 50s are characteristic symptoms. Weakness in the limbs often follows. The disease occurs most often in French-Canadian or Hispanic kindreds.
Oculopharyngeal muscular dystrophy (OPMD)
This type of muscular dystrophy affects adults of both sexes, causing weakness in the eye muscles and throat.
References in periodicals archive
Nuclear accumulation of expanded PABP2 gene product in oculopharyngeal muscular dystrophy
. Muscle Nerve 2000;23(10): 1549-1554.
A South African family with oculopharyngeal muscular dystrophy
: Clinical and molecular genetic characteristics.
Living with oculopharyngeal muscular dystrophy
: A phenomenological study.
Biotechnology company BioBlast Pharma (NasdaqGM:ORPN) reported on Monday the launch of a Phase 3 pivotal study of Cabaletta (trehalose) in Oculopharyngeal Muscular Dystrophy
(OPMD) in the US and Canada.
M2 PHARMA-June 16, 2015-BioBlast Pharma reports Phase 3 pivotal study of Cabaletta in Oculopharyngeal Muscular Dystrophy
patients in the US and Canada