NS that can be associated with other syndromic features such as mental retardation, central nervous system abnormalities, oculocardiac
defects, or skeletal abnormalities is called linear NS syndrome, or Schimmelpenning syndrome (a neurocutaneous phakomatosis).
Topical anesthesia saves the patients from the risks of globe perforations, optic nerve injury, oculocardiac
reflex and above all, the pain and fear perceived because of the peribulbar injections.
Hemorrhage, as well as the oculocardiac
reflex that may result in bradycardia, are two common complications of exenteration that can be fatal for birds.
The body's oculocardiac
reflex, stimulated by gentle pressure on the eyeballs, is another "rest-and-digest" trigger.