octulosonic acid

oc·tu·lo·son·ic ac·id

(ok'tū-lō-son'ik as'id),
The -onic acid formally formed by oxidation of carbon atom 1 of octulose to a carboxylic acid group; a condensation product of d-arabinose and phosphoenolpyruvate analogous to neuraminic acid. It forms part of the repeating unit of the polysaccharides of the complex lipopolysaccharides of the Enterobacteriaceae constituting the characteristic somatic octose antigens.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Extraction and Purification of Lipid A Mild acid hydrolysis of the purified LPS with 1% acetic acid (pH 3.1) at 100 degC for 1 h was used to cleave the ketosidic or 3-deoxy-D-manno-2- octulosonic acid (Kdo) linkage between lipid A and polysaccharide part, while keeping all other aldosidic linkages intact due to their higher acid stability.
In the previous studies, GRAB was expressed either in fusion with large fusion tags such as glutathione S-transferase (CiST) (19), (23) and the CMP -2-keto-3-deoxy octulosonic acid synthetase (CKS) (15) or in fusion with a relatively small tag encoded by the pUET-1 plasmid (16).
Aubert et al used GRA8, amino acid 1-135 produced in fusion with CKS (CMP-2-keto-3-deoxy octulosonic acid synthetase), in kW ELISA and reported a sensitivity of 46.1% (41 of 89 sera) for detection of acute infection in individuals with acute infection (20).