Yohimbine, the [[alpha].sub.2] adrenoceptor antagonist, has been reported to antagonize the antinociceptive effects of nonopioid octacosanol
when assessed using the mouse abdominal constriction test .
Cui, "Measurement of the non-saponifiable matters and octacosanol
in peony seed oil and sunflower seed wax by gas chromatography-mass spectrometry (GC-MS) method," Journal of Agricultural University of Hebei, vol.
In recent years, a number of chemical compounds from NCB were obtained and their structures were identified as acaciin, ursolic acid, octacosanol
, kanshone A, nardosinonediol, nardosinone, [beta]-sitosterol, nardosinanone F, nardosinanone I, kanshone E, narchinol A, narchinol B, and others [15,29].
Preparation of octacosanol
by high vacuum distillation method
Other substances touted as having ergogenic properties are carnitine, cobamamide, growth hormone releasers, octacosanol
, and ginseng, but there is no reliable scientific evidence to support claims that products containing these compounds have ergogenic potential, and heavy supplementation may lead to adverse effects.
Literature survey revealed the presence of diterpenoids , triterpenoids , flavonoids  and chromone glucosides  from different species of the genus Chrozophora and C12-C30 hydrocarbons, cholesterol, stigmasterol, B-sitosterol, B-amyrin, squalin, octacosanol
, hexacosanol and tetracosanol from Chrozophora plicata .
The only fatty alcohol found was octacosanol
([C.sub.28]), which is a compound classified as a terrestrial marker (Volkman, 1986; Bayona et al., 1989; Jeng et al., 2003).
isolated from Tinospora cordifolia downregulates VEG F gene expression by inhibiting nuclear translocation of NF-[alpha] and its DNA binding activity.
One of complementary medicine's greatest unacknowledged supplements is wheat germ, the source from which we derive octacosanol
Apple, 1 medium Ellagic acid, octacosanol
The use of octacosanol
has been investigated by Lazarus A.
(HO-C[H.sub.2]-[[C[H.sub.2]].sub.26]C[H.sub.3]), a long-chain aliphatic alcohol, is the main component of a natural wax product that exists in wheat germ oil, rice bran oil, fruits or leaves (Taylor et al., 2003; de Oliveira et al., 2012).