An alternative to relying on the frozen section process and its inherent inaccuracies would be to routinely stage all women with CAH, knowing that approximately 40% of them have occult cancer
, and more than a third of those will have high-risk features for lymph node metastases.
The relationship between occult cancer
and venous thromboembolism (VTE) has been recognized for many years.
Patients with a blood test showing thrombocytosis should be screened for occult cancer
in women with dense breasts: detection with screening US--diagnostic yield and tumor characteristics.
The decision to pursue supplemental screening should be based on an informed discussion of the patient's individual breast density and cancer risk, as well as an understanding of the likelihood of detecting a mammographically occult cancer
versus false-positive findings that may lead to anxiety, follow-up Imaging, and biopsy.
It's reasonable to assume that the vast majority of cancers identified within a year following diagnosis of a venous leg ulcer were probably present at the time when the ulcer was first diagnosed, meaning venous leg ulcers can serve as a red flag for occult cancer
Today this concept of "Trousseau's syndrome" is used to describe not only migratory thrombosis that precedes the diagnosis of occult cancer
but also any "hypercoagulable state associated with malignant cancer" [3, 4].
This approach leaves men at risk of occult cancer
, leading to a high rate of repeat biopsies, often on cancer-free men.
According to Galena Biopharma, the nelipepimut-S sequence stimulates specific CD8+ cytotoxic T lymphocytes (CTLs) after binding to HLA-A2/A3 molecules on antigen presenting cells and the activated specific CTLs recognise, neutralise and destroy, through cell lysis, HER2 expressing cancer cells, including occult cancer
cells and micrometastatic foci.
Before we can adopt prostate-sparing cystectomies as a routine option for muscle invasive bladder cancer, the potential risk of residual occult cancer
in the prostate must considered.
Washington, Jan 13 (ANI): Scientists have found that the use of preoperative breast MRI detects otherwise occult cancer
with a relatively high degree of accuracy when applied to a diverse population of patients newly diagnosed with breast cancer.
In a retrospective study in 159 women with at least one biopsy-proven cancer, follow-up breast-specific gamma imaging (BSGI) identified clinically and mammographically occult cancer
in 14 of 45 lesions.