The way letters look are processed in the back of the ventral occipitotemporal
cortex but sounds and meanings are processed in an area further forward in that brain region.
The neural mechanisms underlying face-pareidolia perception were proposed to include an interaction between bottom-up processing and top-down processing,4 and accordingly, the brain analyses in this study revealed that both frontal and occipitotemporal
regions were important for processing face pareidolia.
Our results confirmed the clinical picture of alexia without agraphia which arises as a consequence of a lesion in medial occipitotemporal
gyrus in dominant hemisphere , which is also known as an anatomic correlate for Visual Word Form Area (VWFA) .
Bouras, "Object recognition deficit in Alzheimer's disease: possible disconnection of the occipitotemporal
component of the visual system," Neuroscience Letters, vol.
Hypoperfusion may lead to changes in cortical thickness, as obtained from structural MRI scans, in areas most vulnerable to aging (medial prefrontal and pericentral cortices) as well as in areas associated with amyloid-aggregation (e.g., occipitotemporal
and basal temporal cortices), especially in APOE4 carriers .
 showed that patients with Parkinson's disease and mild cognitive impairment (PD-MCI) have a greater grey matter atrophy in both occipitotemporal
and dorsoparietal cortices compared to healthy controls.
The cortical thickness of the right precentral gyrus, which is activated during spatial processing, space and motion perception and imagery, orientation of attention, motor-skill learning , and the execution of motor task , is also found to be greater in Tai Chi practitioners , as is that of the left medial occipitotemporal
sulcus and the lingual sulcus, which are responsible for retrieving and integrating spatial information [34, 36, 37].
demonstrated that the fusiform gyrus, the frontal operculum, occipitotemporal
area, frontomedial cortex, and the amygdala are sensitive to beauty judgements .
The anatomical substrate for prosopagnosia is variably described as left occipitotemporal
area, right fusiform gyrus or a combination of these.
The brain computed tomography showed a 5.3 cm hyperdense lesion over the left occipitotemporal