obtundation


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Related to obtundation: Meningismus, delirium, coma, asterixis

obtundation

 [ob-tun-da´shun]
clouding of consciousness. adj., adj obtun´dent.

ob·tun·da·tion

(obtŭn-dāshŭn)
A condition in which the senses have been dulled by trauma, mistreatment, or psychological stress.
References in periodicals archive ?
Increase of mental obtundation can occur, possibly explained by the preferential movement across the blood brain barrier of C[O.sub.2] compared with bicarbonate.
There were a total of 115 records categorizing the patients into the four neurological groups, with the distribution as follows: Alert, 62 patient times (53.91%); clouding of consciousness, 13 patient times (11.30%); obtundation, 27 patient times (23.48%); and stupor/coma, 13 patient times (11.30%).
The study retrospectively reviewed the medical records of 56 consecutive patients who presented to Tabba Heart Institute, Karachi, from June 2009 to June 2011 with STEMI (defined as electrocardiographic evidence of ST segment elevation of Greater than 1mm in Greater than 2 contiguous leads or new left bundle branch block) who developed cardiogenic shock (defined as presence of systolic blood pressure Less than 90mmHg or need of parenteral inotropic agents with evidence of systemic hypoperfusion like cold clammy skin, cerebral obtundation) within 36 hours of the onset of STEMI, and underwent PPCI within 18 hours of the onset of the shock.
The fifth patient was an otherwise healthy 18-year-old with prolonged obtundation after suspected viral encephalitis.
In more than 100 patients with nonconvulsive status epilepticus (NCSE) at Johns Hopkins Bayview Medical Center, the diagnosis of NCSE was missed or delayed for vanous reasons, such as attributing lethargy and confusion to a postictal state or believing obtundation resulted from alcohol or drugs.
The reports included 80 cases of metabolic acidosis or ketosis, 43 cases of obtundation or confusion, 17 cases of pancreatitis or hyperamylasemia, and 13 patients who died during or shortly after the hyperglycemia episode.
The most common symptoms and signs were nausea/vomiting (10 [71%]), obtundation (nine [64%]), bradycardia (seven [50%]), prolonged unconsciousness (six [43%]), syncope (six [43%]), seizures (four [29%]), confusion (four [29%]), combativeness (four [29%]), respiratory depression (three [21%]), amnesia (two [14%]), and euphoria (two [14%]).
The primary purpose of the present study is to compare the effects of Fentanyl, Nalbuphine and Butorphanol in obtundation of haemodynamic responses during laparoscopic cholecystectomy and secondary aim is to calculate duration of analgesia, sedation score and note any adverse effects.
Patients with Parkinson's Disease or Dementia with Lewy Bodies are reported to have an increased sensitivity to antipsychotic medication, Manifestations of this increased sensitivity include confusion, obtundation, postural instability with frequent falls, extrapyramidal symptoms, and clinical features consistent with the neuroleptic malignant syndrome.
On day 5 of admission, blurred vision and confusion developed and rapidly progressed to obtundation. A repeat head computed tomography scan showed marked edema and transtentorial herniation, and a ventricular drain was placed.
He rapidly developed hypotension, obtundation, and bradycardia.
Obtundation lasting greater than 24 hours has occurred infrequently in .3% of procedures.