The obstructive ventilatory defect
is indicated by the limitation in the airflow, and characterized by reduced [FEV.sub.1], normal or reduced FVC, along with reduced [FEV.sub.1]/FVC.
Obstructive ventilatory defect is seen in 10% of rheumatoid patients since the FEV1/FVC <80% with increased residual volume and total lung capacity ratio.
In RA, obstructive ventilatory defect may be due to airway inflammation.
Majority of them had obstructive ventilatory defect (54.5%).
This significance was high in FEV1 than FVC which characterizes the obstructive ventilatory defect in COPD.
(11) on patients with tuberculous destroyed lung obstructive ventilatory defects were observed in 31 cases (70.5%), followed by mixed ventilatory defect (n=7) and restrictive ventilatory defect (n=5).
The results of pulmonary function tests showed decreased diffusion capacity (n=4), restrictive ventilatory defect (n=3), moderate obstructive ventilatory defect (n=1) and were completely normal in 1 patient.
Clinical characteristics of the cases Clinical characteristics Number of cases (n) Cough 4 Dyspnea 4 Sputum 3 Fever 3 Weight loss 3 Hemoptysis 1 Bilateral inspiratory crackles 4 Normal physical examination 1 Decreased diffusion capacity 4 Restrictive ventilatory defect 3 Obstructive ventilatory defect 1 Normal pulmonary function 1 Bilateral infiltrations 4 Focal opacity 1 Transthoracic biopsy 4 Transbronchial biopsy 1 All the patients were classified as cryptogenic, except a 49-year-old woman who presented with normocapnic respiratory failure and acute renal failure.
The 2012-GLI and 2006-Hong Kong equations may lead to missed diagnoses of obstructive ventilatory defects
and the small airway dysfunction, while traditional linear equations for all ages may lead to overdiagnosis.
Obstructive ventilatory defects
were the most common abnormality, and these were found in 35 of 47 (75%).