nutritional bone disease

nutritional bone disease

A nonspecific term for any bone disease and deformity due to disorders of nutrition, bone and mineral metabolism, which result in osteomalacia of rickets, anorexia nervosa/starvation-related osteopenia and/or osteoporosis, and others.
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In the March 2008 issue of the Journal, Teotia and Teotia reviewed their extensive experience of nutritional bone disease in India gained through over 40 yr of research in the field (1).
18) The inability of elderly women to adequately increase calcium intake to suppress secondary hyperparathyroidism makes it difficult to distinguish age-related bone loss from nutritional bone disease.
30) The low correlation of calcium intake with dietary fiber deserves attention, since diets higher in various fiber components impair the absorption of calcium and may thereby accelerate nutritional bone disease in the elderly.
Data on nutritional bone disease are described and discussed.
Nutritional bone disease is defined as a syndrome of bone disease and deformities in which the bone is affected as a tissue, primarily as a consequence to deficiencies of vitamin D and calcium; or imbalances of the nutrients which are critically important for the growth and development of the bone; its mineralization and maintenance of calcium homeostasis and the structural integrity and health of the skeleton.
The epidemiological spectrum of nutritional bone disease is summarized in Table I.
Nutritional (privational) vitamin D-deficiency osteomalacia is the commonest nutritional bone disease prevalent in Indian mothers and is characterized by a failure to mineralize the newly formed organic matrix (osteoid) of bone in a normal manner.
Despite having a large series of patients with nutritional bone disease, we are still missing the valuable knowledge to our experience with vitamin D intoxication.
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