nude mouse


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mouse

 [mows]
a small rodent, various species of which are used in laboratory experiments.
1. a small loose body.
2. a computer pointing device.
joint mouse a movable fragment of synovial membrane, cartilage, or other body within a joint; usually associated with degenerative osteoarthritis and osteochondritis dissecans.
knockout mouse a mouse that has had a specific gene artificially deleted from its genome.
nude mouse a mouse homozygous for the nu gene; these mice are hairless, lack a thymus, and thus lack T lymphocytes.
peritoneal mouse a free body in the peritoneal cavity, probably a small detached mass or omentum, sometimes visible radiographically.
SCID mouse (severe combined immunodeficiency) a strain of mice lacking in T and B lymphocytes and immunoglobulins, either from inbreeding with an autosomal recessive trait or from genetic engineering, used as a model for studies of the immune system.

nude mouse

a hairless mutant mouse with thymic hypoplasia, lacking T cells.
A mutant strain of lab mouse that is hairless, thymusless due to congenital thymic aplasia, and T cell-less.
References in periodicals archive ?
For our study, we chose to use an athymic nude mouse model to preclude the possibility of an immunologic rejection of the human septal cartilage.
In order to obtain xenograft tumours 1x[10.sup.7] NT8e tumour cells in 100 [micro]l Hanks balanced salt solution (HBSS) were injected subcutaneously on the dorsal right flank of the nude mouse as described earlier (8,9).
In the article titled "A Versatile Orthotopic Nude Mouse Model for Study of Esophageal Squamous Cell Carcinoma" [1], the authors' affiliations were incorrectly listed.
The combination therapy was more effective than either of the two gene vectors alone when transfected into HepG2 cells and the HCC nude mouse model.
An aliquot (100 [micro]L) containing 5 x [10.sup.6] Capan-1 cells in IMDM was injected subcutaneously in the right upper flank of each nude mouse. Tumors were allowed to grow in vivo for 25 days after the inoculations, with a tumor diameter of no more than 10 mm being obtained at this time.
found in nude mouse skin in vitro that niosomes appear to be feasible as a delivery vehicle for the dermal administration of black tea extracts as a sunscreen agent.
Kubota, "Metastatic models of human cancer xenografted in the nude mouse: the importance of orthotopic transplantation," Journal of Cellular Biochemistry, vol.
A bacillary suspension prepared from nude mouse footpads of this generation was provided to Dr.
In addition to the crude AL extract, acute and subacute toxicity of [beta]-eudesmol was also evaluated in mice in order to find the MTD and MOAEL levels for further investigation of its anti-CCA activity and pharmacokinetics in CCA-xenografted nude mouse model [27].
The MCF-7/ADM cells (1 x [10.sup.6]/mouse) were subcutaneously injected into the left armpit of each nude mouse. Fifteen days after inoculation, the implanted tumors became palpable, and the experimental treatments were initiated.
Thus, we examined biophysical properties of SS-PEI/VEGF-siRNA complexes, in vivo biodistribution of the complexes, siRNA transfection in vitro and in vivo, and growth inhibition of HCC tumor bearing in a nude mouse model.