nucleotide

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nucleotide

 [noo´kle-o-tīd]
any of a group of compounds obtained by hydrolysis of nucleic acids, consisting of a purine or pyrimidine base linked to a sugar (ribose or deoxyribose), which in turn is esterified with phosphoric acid.
cyclic n's those in which the phosphate group bonds to two atoms of the sugar forming a ring, as in cyclic AMP and cyclic GMP, which act as intracellular second messengers.

nu·cle·o·tide

(nū'klē-ō-tīd),
Originally a combination of a (nucleic acid) purine or pyrimidine, one sugar (usually ribose or deoxyribose), and a phosphoric group; by extension, any compound containing a heterocyclic compound bound to a phosphorylated sugar by an N-glycosyl link (for example, adenosine monophosphate, NAD+). For individual nucleotides see specific names.
Synonym(s): mononucleotide

nucleotide

/nu·cleo·tide/ (noo´kle-o-tīd″) one of the compounds into which nucleic acid is split by action of nuclease; nucleotides are composed of a base (purine or pyrimidine), a sugar (ribose or deoxyribose), and a phosphate group.
cyclic nucleotides  those in which the phosphate group bonds to two atoms of the sugar forming a ring, as in cyclic AMP and cyclic GMP, which act as intracellular second messengers.

nucleotide

(no͞o′klē-ə-tīd′, nyo͞o′-)
n.
Any of a group of compounds consisting of a nucleoside combined with a phosphate group and constituting the units that make up DNA and RNA molecules.

nucleotide

[no̅o̅′klē·ətīd′]
a compound consisting of one or more phosphate groups, a pentose sugar, and a nitrogenous base. Chains of nucleotides form DNA and RNA; free nucleotides, such as adenosine triphosphate and guanosine triphosphate, are important energy carriers in all cells.

nu·cle·o·tide

(nū'klē-ō-tīd)
A combination of a (nucleic acid) purine or pyrimidine, one sugar (usually ribose or deoxyribose), and a phosphoric group.
Synonym(s): mononucleotide.

nucleotide

A molecule formed from the bonding of a purine or a pyrimidine base with a sugar and a mono-, di- or tri-phosphate group. Compare NUCLEOSIDE. Four different nucleotides may polymerize to form DNA. They are 2'-deoxyadenosine 5'-triphosphate; 2'-deoxyguanosine 5'-triphosphate; 2'-deoxycytidine 5'-triphosphate; and 2'-deoxythymidine 5'-triphosphate. These lengthy names are commonly abbreviated to dATP, dGTP, dCTP and dTTP. Even this is too clumsy when printing out the sequence of nucleotides in a length of DNA. In that case they are abbreviated to A, G, C and T (for adenine, guanine, cytosine and thymine). In RNA the sugar is not 2'-deoxyribose, but ribose itself. Also one of the RNA bases differs from that in DNA. Thymine is replaced by uracil. So the nucleotides of RNA are adenosine 5'-triphosphate; guanosine 5'-triphosphate; cytidine 5'-triphosphate; and uridine 5'-triphosphate. These are abbreviated to ATP, GTP, CTP and UTP or simply A, G, C and U.
Nucleotideclick for a larger image
Fig. 232 Nucleotide . Basic units of (a) deoxyribose sugar, (b) phosphate. Each carbon atom is numbered (1 prime, 2 prime, etc).
Nucleotideclick for a larger image
Fig. 233 Nucleotide . Linkage of the three nucleotide elements.

nucleotide

a complex organic molecule forming the basic unit of NUCLEIC ACIDS, with a structure made up of three components: a pentose sugar (ribose, or deoxyribose with one less oxygen atom), an organic base (PURINE type: ADENINE and GUANINE; or PYRIMIDINE type: CYTOSINE, THYMINE and URACIL) and a phosphate group (see Fig. 232 ). The three elements are linked together by two condensation reactions between the 1 sugar carbon and a base forming a NUCLEOSIDE, and the 5' sugar carbon and the phosphate (see Fig. 233 ). The nucleotides are formed into POLYNUCLEOTIDE CHAINS.

Nucleotide

Any of a group of organic molecules that link together to form the building blocks of DNA or RNA.
Mentioned in: Myotonic Dystrophy

nucleotide

combination of nucleic acid, purine or pyramidine, sugar (ribose or deoxyribose) and a phosphate group

nucleotide

any of a group of compounds obtained by hydrolysis of nucleic acids, consisting of a purine or pyrimidine base linked to a sugar (ribose or deoxyribose), which in turn is esterified with phosphoric acid. See also nucleoside, deoxyribonucleic acid.

cyclic n's
those in which the phosphate group bonds to two atoms of the sugar forming a ring, as in cyclic AMP and cyclic GMP, which act as intracellular second messengers.
nucleotide sequences
see dna sequencing.
single nucleotide polymorphisms (SNPs)
single base pair changes that distinguish one individual from another of the same species.
References in periodicals archive ?
AB890001 and AB890374), and nucleotide sequence identity was 99.
By comparing the DNA nucleotide sequence of the target gene from a tissue biopsy (or other source of DNA) to the normal gene sequence in databases, the presence or absence of genetic mutations can be documented.
Comparison of the nucleotide sequences of rRNA genes has been widely used for establishing evolutionary relationships among a wide variety of species.
In addition, there are similarities in the 4 genes analyzed in this study between SKA-1 and the novel group of human rotaviruses: 1) nucleotide sequences and nucleotide numbers of noncoding regions at the 5' and 3' ends are similar to each other; 2) lengths of nucleotide and deduced amino acid sequences are similar to each other; and 3) phylogenetic analysis showed that these viruses are in the same cluster.
The sense strand contains the nucleotide sequence for the amino acid sequence of a protein.
8% nucleotide sequence identity in this part of the genome, which shows the great diversity of this region.
Johnston, IA) has patented compositions and methods for regulating expression of heterologous nucleotide sequences in a plant.
The nucleotide sequences were determined by automatic dideoxy cycle sequencing techniques (Applied Biosystems, Foster City, CA, USA).
For each DNA sample, the researchers determined the nucleotide sequences of several genes and then used computers to assess the similarity of the sequences among the 26 species.
The process of protein synthesis (also known as translation, which refers to the translating of the nucleotide sequences of nucleic acids (genes) to the amino acid sequences of proteins), is a vital component in cell growth and completion of the cell's proliferative cycle.
Nucleotide sequences from this study were deposited into GenBank (DQ317539-DQ317561).
Some of the most striking evidence cited by out-of-Africa supporters comes from Neandertals' mitochondrial DNA, which contains nucleotide sequences that differ considerably from those of modern humans (SN: 7/19/97, p.

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