nucleotidase


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nucleotidase

 [noo″kle-o-ti´dās]
an enzyme that splits nucleotides into nucleosides and phosphoric acid.

nucleotidase

(no͞o′klē-ə-tī′dās, -dāz, nyo͞o′-)
n.
An enzyme that catalyzes the hydrolysis of a nucleotide to a nucleoside and phosphoric acid.

nucleotidase

an enzyme that catalyses the hydrolysis of a nucleotide to a nucleoside and orthophosphate.
References in periodicals archive ?
ciliata decreased the levels of tumor markers: aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, alpha-fetoprotein, gamma glutamyl transferase, 5' nucleotidase and glucose-6-phosphate dehydrogenase.
There were a significant positive correlations between alkaline, acid DNase activity and Ecto-5-prime nucleotidase with serum lead in group A [Iraqi workers employed on the operation of diesel generators] as shown in table 6.
Iqbal, "Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ectonucleotide pyrophosphatase/phosphodiesterase, ecto-5'nucleotidase, and alkaline phosphatase inhibitors," Medicinal Research Reviews, vol.
In the Ap and N-9 treated groups the number of acrosome reacted cells were found to be high and it also caused agglutination of the sperms indicating the loss of intactness of the plasma membrane which was further supported by the significant reduction in the activity of membrane bound 5' nucleotidase and acrosin enzyme.
Cells were found negative for the lymphocyte-related CD45 (protein tyrosine phosphatase) and slightly positive for SSEA4 (stage-specific embryonic antigen 4), while they significantly express CD90 (Thy-1), CD73 (5' nucleotidase), CD29 (integrin [beta]1), and CD105 (endoglin), thus identifying a mesenchymal stem cell population.
B-A reduces the elevated levels of serum alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), [gamma]-glutamyl transferase ([gamma]-GT), lactate dehydrogenase (LDH), 5' nucleotidase (5'ND).
Drug inactivation can result from Ara-CMP conversion into Ara-uracil by cytidine deaminase (cdd), or from dephosphorylation of Ara-CMP by cytoplasmic nucleotidase (3).
Antibody Alternate name Reactivity CD29 (1) Integrin beta 1 PE rabbit anti-human CD44 (2) H-CAM, PGP-1 FITC mouse anti-sheep CD45 (1) Leukocyte common FITC mouse anti-sheep antigen CD73 (1) NT5E, 5' nucleotidase, APC mouse anti-human E5NT, eNT, NT, NT5 CD90 (1) Thy-1 FITC mouse anti-human CD105 (1) Endoglin, ENG, END, PE mouse anti-human HHT1, ORW, ORW1 CD166 (1) ALCAM PE mouse anti-human Antibody Identical amino acid Volume [[micro]L] per residues between man test (in 100 [micro]L PBS) and sheep (%) (3) CD29 (1) 93 10 CD44 (2) -- 5 CD45 (1) -- 10 CD73 (1) 81-89 3 CD90 (1) -- 3 CD105 (1) 70-75 3 CD166 (1) 90 10 (1) BD Biosciences, Beckton Dickinson, Franklin Lakes, USA.
In this work, we analyzed the nucleotidase activities of purified hPAP in comparison to recombinant CD73 in vitro and, further, ex vivo by using lymphoid cell suspensions isolated from wild type, CD73 and PAP knockout, and CD73/PAP double knockout mice, as well as mouse lymph nodes and human tonsils cryosections as enzyme sources.
Webster, "Lymphocyte purine 5 nucleotidase deficiency in primary hypogammaglobulinaemia," The Lancet, vol.
Laboratory results since her referral included vitamin B12 245 ng/L [reference interval (RI), 251911 ng/L], iron 370 ug/L (RI, 400-1450 [micro]g/L), anti-tTG IgA 13 AU (RI, 0-20 AU), and 5' nucleotidase 22.1 U/L (RI, 4.0-11.5 U/L).
In this assay, lithium is determined through a kinetic coupling system involving a lithium-sensitive enzyme, 3',5'-bisphosphate nucleotidase, from yeast.