There were a significant positive correlations between alkaline, acid DNase activity and Ecto-5-prime nucleotidase
with serum lead in group A [Iraqi workers employed on the operation of diesel generators] as shown in table 6.
The activity of 5' nucleotidase
was determined by measuring the rate of release of inorganic phosphate from adenosine 5' monophosphate according to Heppel and Hilmoe (1964).
Alanine transaminase (ALT), aspartate transaminase (AST) (Reitman and Frankel, 1957), alkaline phosphatase (ALP) (King, 1965a), 5' nucleotidase
(5'ND) (Luly et al.
Chemoresistance to Ara-C can arise from a number of factors influencing the rate of Ara-CTP formation and incorporation into DNA (5), including low drug uptake, conversion into Ara-uracil by cytidine deaminase, or dephosphorylation of active metabolite by cytoplasmic nucleotidase
In this assay, lithium is determined through a kinetic coupling system involving a lithium-sensitive enzyme, 3',5'-bisphosphate nucleotidase
, from yeast.
The proinflammatory signaling of extracellular ATP is terminated by nucleotidases
active in the interstitial fluid and the membrane-bound ectonucleotidases, CD39 and CD73 (Fig.
Among hydrolytic enzymes proteases phospholipases (PLA) were more screened pharmacologically whilst nucleases nucleotidases
and phosphatases (acidic as well as alkaline phosphatases) were less characterized (Matsui et al.
SGPT, Serum Bile acid, GGPT and Serum nucleotidases