nucleosome


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nucleosome

 [noo´kle-o-sōm″]
any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.

nu·cle·o·some

(nū'klē-ō-sōm'),
A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage.
Synonym(s): nu body
[nucleo- + G. sōma, body]

nucleosome

/nu·cleo·some/ (-sōm) any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.

nucleosome

(no͞o′klē-ə-sōm′, nyo͞o′-)
n.
Any of the repeating subunits of chromatin found in eukaryotes, consisting of a DNA chain coiled around a core of histones.

nu′cle·o·som′al (-sō′məl) adj.

nucleosome

[no̅o̅′klē·əsōm′]
Etymology: L, nucleus + Gk, soma, body
any one of the repeating DNA-histone complexes that appear as beadlike structures at distinct intervals along a chromosome.

nucleosome

A nucleic acid and protein complex, which is the basic structural unit of chromatin, composed of a segment of DNA wrapped around a core of histone molecules.

nu·cle·o·some

(nū'klē-ō-sōm)
A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage.
[nucleo- + G. sōma, body]

nucleosome

The structural subunit of CHROMATIN consisting of about 200 BASE PAIRS and a barrel-shaped core of eight histone protein molecules (an octamer).

nucleosome

the basic structural unit of the eukaryote chromosome, being composed of four pairs of HISTONE proteins (H2A, H2B, H3 and H4) that are combined to form an octomer around which is wrapped about 150 nucleotide pairs of DNA.

nucleosome

any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.
References in periodicals archive ?
MNase-Real-Time Quantitative Polymerase Chain Reaction to Determine Nucleosome Occupancy
They then introduced the mutated protein in blood stem cells, and found that the mutated DPF2 could no longer bind to the nucleosome.
Npm could promote in vitro nucleosome formation, also participate in the decondensation process that the highly compacted sperm chromatin undergoes after fertilization (Loyola and Almouzni, 2004).
The WPS represents the protection that a DNA fragment could receive from being bound to a nucleosome or transcription factor.
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding.
What scientists have found is that DNA is not regularly packaged with nucleosomes, instead nucleosomes are assembled in groups of varying sizes, called "nucleosome clutches" because of their similarity to egg clutches.
H2B, H2A (two dimmer form) and H3, H4 (one tetra dimmer form) form nucleosome.
Crystal Structure of the Nucleosome Core Particle at 2.
The NuQ range of products is based on the Nucleosomics platform, which identifies and quantifies nucleosome structural features such as histone modifications and variations, DNA methylation patterns and nucleosome-protein adducts.
The fundamental unit of chromatin is the nucleosome, where 146 bp of DNA are wrapped around a histone octamer core, comprised of two of each core histones, H2A, H2B, H3 and H4, while its structure is completed with the association of H1 linker histone (Wolffe & Guschin, 2000).
2]] that serves as a core around which approximately 146 bp of DNA are wrapped, forming the most basic repetitive subunit of chromatin, the nucleosome core particle (van Holde, 1988).
Both DNA and protein components of the nucleosome are subject to a variety of modifications that can influence chromatin conformation and accessibility.