nucleoside diphosphate

nu·cle·o·side di·phos·phate (NDP),

the pyrophosphoric ester of a nucleoside, that is, a nucleoside in which the H of one of the ribose hydroxyls (usually the 5') is replaced by a pyrophosphoric (diphosphoric) radical, for example, adenosine 5'-diphosphate. Compare: nucleoside bisphosphate.
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References in periodicals archive ?
Dynamics of the nucleoside diphosphate kinase protein DYNAMO2 correlates with the changes in the global GTP level during the cell cycle of Cyanidioschyzon merolae Yuuta IMOTO, Yuichi ABE, Kanji OKUMOTO, Mio OHNUMA, Haruko KUROIWA, Tsuneyoshi KUROIWA, M.J.A.
Antiviral nucleoside diphosphate diglycerides: improved synthesis and facilitated purification.
tuberculatum venom can be grouped basically into proteins involved in insect metabolism (annexin B9, nucleoside diphosphate kinase; aconitate hydratase; superoxide dismutase; triose phosphate isomerase; glyceraldehyde-3phosphate dehydrogenase; succinyl-CoA ligase; fructosebisphosphate aldolase; arginine kinase; citrate synthase; enolase; ATP synthase; 4-hydroxybutyrate coenzyme A transferase; medium-chain specific acyl-CoA dehydrogenase, and isocitrate dehydrogenase); transport protein (transferrin); and structural proteins (cyclophilin, actin, and chitinase).
In humans, there are 10 genes belonging to the NM23 gene family, of which the two most abundantly expressed are NM23-H1 and NM23-H2 that encode the A and B subunits of nucleoside diphosphate kinase, respectively [9].
gingivalis can inhibit the extracellular ATP- P2X7 pathway by directly preventing inflammasome activation through secreting an effector called 'nucleoside diphosphate kinase'.
The NSP2 protein functions as a single-stranded RNA binding protein, nucleic acid helix destabilizer, nucleoside triphosphatase (NTP), nucleoside diphosphate kinase (NDP), and RNA triphosphatase (RTPase) (2).
The drug requires phosphorylations to monophosphate and diphosphate (active) forms by pyrimidine nucleoside diphosphate kinase and nucleoside diphosphate kinase, respectively.
The gene is located on chromosome locus 17q21, which encodes an 18.5 kDa protein containing 166 amino acid residues with nucleoside diphosphate kinase, histidine kinase and serine autophosphorylation activities [4].
These confirmed proteins include cathepsin D, nucleoside diphosphate kinase 1, fatty acid binding protein 5, oncogene DJ1, and peroxiredoxin 5.
Ridge, Nucleoside Diphosphate Kinase from Bovine Retina.
In terms of dynamin-based machineries, recent studies have demonstrated the function of the nucleoside diphosphate kinase (NDPK) proteins in GTP synthesis.
Proteomic analysis of postmortem cerebrospinal fluid identified nucleoside diphosphate kinase A and PARK7 as proteins released by brain injury and as potential new biomarkers for stroke (13).

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