are usually administered for at least 6 months after the patient has developed anti-HBe, in HBeAg-positive patients, and until clearance of HBsAg in HBeAgnegative patients.
These preliminary data provide promise that the combination of Combivir+Ziagen may effectively suppress HIV replication in patients previously treated with other nucleoside analogues
," said Keith Henry, M.
Clinical data indicated that patients receiving indinavir alone or in combination with nucleoside analogues
experienced a marked increase in their CD4 levels and had a marked decrease in their viral load.
are used and developed for the treatment of several life threatening viral infections, including HIV-1 and HCV.
Approved June 24, 1996 for use in combination with nucleoside analogues
for the treatment of HIV-infected adults experiencing clinical and/or immunologic deterioration.
Patient access to current and new nucleoside analogues
is improving and more patients are anticipated to gain access to drug treatments.
five who received nucleoside analogues
and 18 who were untreated (Lancet 362:1708-13, 2003).
A trend toward higher weight loss was seen in patients who received didanosine or stavudine, compared with those who received other nucleoside analogues
This combination product should only be used by those whose treatment regimens would otherwise include these doses of these three nucleoside analogues
Investigators reported results of a 24-week, Phase IIB, Merck-sponsored study of MK-0518 in patients with resistance to protease inhibitors, nucleoside analogues
and non-nucleoside analogues
Quadruple therapy with two nucleoside analogues
plus nelfinavir and efavirenz improved treatment response in a recent study of HIV-infected patients who failed treatment with nucleoside analogues
NNRTIs, nucleoside analogues
, protease inhibitors), across classes, and with HIV positive patients who are not receiving therapy.