nucleoside analog reverse transcriptase inhibitor


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nucleoside analog reverse transcriptase inhibitor

NRTI, NARTI, "nuke" AIDS A class of drugs that includes AZT–Retrovir, ddI–Videx, ddC–HIVID, d4T–Zerit, 3TC–Epivir, abacavir–Ziagen; reverse transcriptase is the part of HIV that assembles viral DNA; NRTIs inhibit reverse transcriptase by acting as 'dummy' nucleosides. See AIDS.
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The program makes PREVEON available free of charge to HIV infected adults in the United States who have failed treatment with at least two nucleoside analog reverse transcriptase inhibitors and one protease inhibitor.
Program Design -- The program will make PREVEON available free of charge to HIV-positive patients at least 13 years of age who have failed treatment with at least two nucleoside analog reverse transcriptase inhibitors and one protease inhibitor, and who have had, within the past two months, a CD4 count less than or equal to 50 cells/mm3 and an HIV RNA level of greater than or equal to 30,000 copies/mL by PCR.

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