nucleoside analog reverse transcriptase inhibitor


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nucleoside analog reverse transcriptase inhibitor

NRTI, NARTI, "nuke" AIDS A class of drugs that includes AZT–Retrovir, ddI–Videx, ddC–HIVID, d4T–Zerit, 3TC–Epivir, abacavir–Ziagen; reverse transcriptase is the part of HIV that assembles viral DNA; NRTIs inhibit reverse transcriptase by acting as 'dummy' nucleosides. See AIDS.
References in periodicals archive ?
Reverset was also shown to be effective in patients with virus resistant to other commonly used nucleoside analog reverse transcriptase inhibitors (NRTIs), including viruses harboring multiple thymidine analog mutations (TAMS), including the M41L and L210W mutations, and the L74V and M184V mutations.
Ototoxicity associated with the use of nucleoside analog reverse transcriptase inhibitors: a report of 3 possible cases and review of the literature.
Nucleoside analog reverse transcriptase inhibitors (NRTIs), the first antiretroviral agents to be introduced to the market back in 1987, remain a mainstay of anti-HIV therapy.

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