NXN

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NXN

A gene on chromosome 17p13.3 that encodes nucleoredoxin, which functions as a redox-dependent negative regulator of the Wnt signalling pathway. Nucleoredoxin may act as a transcription regulator and regulate phosphatase 2A.
References in periodicals archive ?
Miki, "Redox regulation of Wnt signalling via nucleoredoxin," Free Radical Research, vol.
Carrageenan exposure and ROS production inhibited thioredoxin reductase activity and increased oxidation of nucleoredoxin.
common food additive carrageenan stimulates wnt/beta-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction.