Histiocytoid cells with large, vesicular nuclei and "inclusion-like" nucleoli
that mimic Reed-Sternberg cells are characteristic of myxoinflammatory fibroblastic sarcoma and can be found in most tumors (hematoxylin-eosin, original magnification X600).
Thymic cortical epithelial cells have abundant cytoplasm, vesicular nuclei with finely divided chromatin and small nucleoli
, and cytoplasmic filaments that contact adjacent cells.
However, in the present study, moderate correlation was found between cell size, cell uniformity, presence of nucleoli
and tumor aggressiveness.
Literature reports that increased cytoplasmic eosinophilia, multinucleated hepatocytes (mostly binucleated), prominent nucleoli
and two cell thick liver cords seen in group C animals are suggestive of regeneration.
In the stage II, the oocytes had highly basophilic cytoplasm and nucleoli
, associated with intense protein synthesis (Takahashi, Gointein & Nakaghi, 2008).
2 Photomicrographs show a tumour composed of variably sized tubules (a: Hematoxylin and eosin stain [H&E] x100) and cystic spaces (b: H&E x100) that are separated by thin, hypocellular fibrovascular septae (c: H&E x200), with the lining epithelium showing tombstone appearance focally (d: H&E x200); the tubules are lined by atypical cuboidal to pseudostratified ciliated columnar cells (arrow) with abundant eosinophilic cytoplasm (e: H&E x400), large round to ovoid nuclei with prominent nucleoli
(f: H&E x400) and hobnail appearance (g: H&E x600); solid areas show smaller tubules lined by similar atypical cells in a sclerotic stroma (h: H&E x200; i: H&E x400).
The cells had round eccentric nuclei, conspicuous nucleoli
, abundant eosinophilic cytoplasm and paranuclear inclusions (Fig.
The nuclei were vesicular with small or indistinct nucleoli
At 24 hours the nuclei of the tumor cells appeared small and shrunken with disrupted nuclear membranes, markedly condensed chromatin and obscured nucleoli
Cells were monomorphic, with large hyperchomatic eccentrically placed nuclei with multiple nucleoli
Histological analysis of Leptobotia elongata Bleeker ovaries revealed five stages in oocyte development (oogonia, previtellogenic oocytes, vitelline vacuolated oocytes, vitellogenic oocytes and mature oocytes) based on nucleoli
, follicle cells and vitellogenesis.
The cells have ovoid, vesicular nuclei, finely granular and evenly distributed chromatin, small nucleoli
and abundant cytoplasm with vacuolization at places (Figure 2).