nucleocytoplasmic ratio


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nucleocytoplasmic ratio

the ratio of the volume of a nucleus of a cell to the volume of the cytoplasm. The proportion is usually constant for a specific cell type, and an increase is indicative of malignant neoplasms. Also called karyoplasmic ratio, nucleoplasmic ratio.
References in periodicals archive ?
In summary, this case illustrates that several of the key criteria used for a diagnosis of TIC can be seen in papillary syncytial metaplasia of tubal mucosal endometriosis, including marked epithelial stratification with loss of polarity, increased nucleocytoplasmic ratio, and rounded nuclei with chromatin clearing and prominent nucleoli.
Although occasional cells showed ultrastructural intermediate features between the undifferentiated and glandular cell types (large size and high nucleocytoplasmic ratio but a well-developed endoplasmic reticulum, a prominent Golgi complex, and few secretory granules), in general, there was an abrupt transition between the 2 components.