nucleocytoplasmic ratio


Also found in: Encyclopedia.

nucleocytoplasmic ratio

the ratio of the volume of a nucleus of a cell to the volume of the cytoplasm. The proportion is usually constant for a specific cell type, and an increase is indicative of malignant neoplasms. Also called karyoplasmic ratio, nucleoplasmic ratio.
References in periodicals archive ?
Imprint smear from the ulcer showed mainly necrosis and few cells with high nucleocytoplasmic ratio.
Peripheral blood neutrophils [12] are showed striking dysplastic [12] features, which included detached nuclear fragments, acquired Pelger-Huet anomaly chromatin clumping, neutrophils with strangely shaped nuclei, and a high nucleocytoplasmic ratio and macropolycytes.
The epithelium within this pseudopapillary lesion showed an increased nucleocytoplasmic ratio, round large nuclei, and prominent nucleoli (Figure 1, B).
7,15) Histologic features of malignant GCTs include necrosis, spindling, vesicular nuclei with prominent nucleoli, high nucleocytoplasmic ratio, cellular pleomorphism, and mitotic figures (>2 mitoses/10 HPF).
Important cytological criteria useful in distinguishing HCC from non-neoplastic liver are increased nucleocytoplasmic ratio, arrangement of tumor cells in trabecular pattern and atypical naked hepatocytic nuclei.