nucleocapsid


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nucleocapsid

 [noo″kle-o-kap´sid]
a unit of viral structure, consisting of a capsid with the enclosed nucleic acid; it is generally inside the cytoplasm.

vi·ri·on

(vī'rē-on, vir'ē-on),
The complete virus particle that is structurally intact and infectious.

nucleocapsid

/nu·cleo·cap·sid/ (noo″kle-o-kap´sid) a unit of viral structure, consisting of a capsid with the enclosed nucleic acid.
Enlarge picture
Nucleocapsid in a schematic diagram of HIV-1; molecules of protease, integrase, and reverse transcriptase, which also occur within the capsid, are omitted for simplicity.

nucleocapsid

(no͞o′klē-ō-kăp′sĭd, nyo͞o′-)
n.
The nucleic acid of a virus together with the protein coat that encloses it.

nucleocapsid

[no̅o̅′klē·ōkap′sid]
Etymology: L, nucleus + capsa, box
a viral enclosure consisting of a capsid or protein coat and a nucleic acid that it surrounds. Some viruses consist solely of bare nucleocapsids; others have more complex enclosures.

vi·ri·on

(vī'rē-on)
The complete virus particle that is structurally intact and infectious.

nucleocapsid

a minimum unit of viral structure, consisting of a protein capsid with the enclosed nucleic acid. For some viruses the nucleocapsid is enclosed within an envelope.
References in periodicals archive ?
Measles virus nucleocapsid protein binds to FcgammaRII and inhibits human B cell antibody production.
Of the total proteins, 21 have been found in the envelope, 10 in the nucleocapsid and 5 in the tegument (putative structure located between the envelope and nucleocapsid).
a) Cell culture supernatant; (b) recombinant nucleocapsid protein produced in yeast cells; (c) clinical specimen tested positive by specific PCR; (d) bacterial colony.
Detection of Puumala hantavirus antibody with ELISA using a recombinant truncated nucleocapsid protein expressed in Escherichia coli.
The pattern of accumulation of labeled antibodies against NS3 and N-protein resembled that of the viral nucleocapsid protein in mesophyll cells, as previously described by Espinoza et al.
Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in SARS patients by enzyme-linked immunosorbent assay.
There were 162 capsomers per nucleocapsid (capsomeres hexagonal in cross-section with a hole atoning halfway down the long axis).
Serodiagnosis and serosurveillance of SARS (10,11) have revealed that nucleocapsid (N) protein-specific antibodies in the serum of SARS patients have higher sensitivity (12-14) and longer persistence (9) than those of other structural proteins of SARS-CoV.
ALN-RSV01 is a small interfering RNA (siRNA) that is designed to selectively and potently silence the RSV nucleocapsid 'N' gene.
Chest cavity lavage samples of voles were investigated by IgG ELISA using a recombinant nucleocapsid protein of PUUV (6).
Utilization of autopsy tissue RNA for the synthesis of the nucleocapsid antigen of a newly recognized virus associated with hantavirus pulmonary syndrome.
We amplified the complete nucleocapsid proteinencoding region for 3 of the 5 samples positive by RT-PCR with 3 primer pairs: PuNCRS (5'-TAGTAGTAGACTCCTTGAA-3')/Pu255R (5'-TGGACACAG CATCTGCCA-3'), Pu40F (5'-CTGGAATGAGTGACTTAAC-3')/Pu393R (5'-TATGGTAATGTCCTTGATGT-3'), and Pu1027F (5'-ATGGCAGAGTTAGGTGCA-3')/Pu1779R (5'-TCAGCATGTTGAGGTAGT-3').

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