RCA is a highly sensitive nucleic acid amplification technique
, which has been used in the detection of DNA, RNA, single-nucleotide polymorphisms, and other biological species.
This screening procedure is a justifiable compromise among competing factors: the sensitivities of nucleic acid amplification technique
assays, the diagnostic window period, and delay in delivery of the PC supply.
The WNV assay was developed using Gen-Probe's family of technologies, including a unique nucleic acid amplification technique
called Transcription-Mediated Amplification (TMA).
The superior sensitivity of nucleic acid amplification technique
(NAT)  enables diagnosis of infectious diseases at an early stage before positive serologic results indicate an infection (1).
SDA is another non-PCR nucleic acid amplification technique
, developed in 1991 [145, 146].
Nucleic acid amplification techniques
(NAATs) for clinical virology have seen rapid development in the past decade.
Working reagents for nucleic acid amplification techniques
from DNA Technology of Brazil were used to establish the analytical sensitivity of the multiplex assay.
We identified PARV4 in such pools (5), albeit at a lower frequency and titer than parvovirus B19, when parvovirus B19 was not excluded by screening with nucleic acid amplification techniques
The patented technology was invented in the mid-1980's and relates to pathogen detection methods that achieve high clinical sensitivity by coupling Vysis' reversible target capture technology with enzymatic nucleic acid amplification techniques
, such as the polymerase chain reaction, Q-beta replicase, and transcription mediated amplification.
Additional testing such as nucleic acid amplification techniques
for specified viruses and reverse transcriptase assays for retroviruses should complement nonspecific tests.
The rationale behind immuno-PCR is to develop ultrahigh-sensitivity labels by exploiting the extremely high productivity of nucleic acid amplification techniques
, coupled with highly sensitive approaches to detect the amplified material.