Nucleated erythrocyte | definition of nucleated erythrocyte by Medical dictionary
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nucleated erythrocyte A red cell with a nucleus, which is usually lysed before the reticulocyte stage of RBC maturation. Scattered nucleated erythrocytes are a normal finding in the peripheral blood of newborns, but distinctly abnormal in adults and seen in thalassemia major or leukoerythroblastic reactions; in the foetus, > 5/100 NRBCs in the circulation is typically seen with hypoxia.
having a nucleus or nuclei.
References in periodicals archive
Fate of fetal nucleated erythrocytes
circulating in maternal blood: apoptosis is induced by maternal oxygen concentration [Technical Brief].
in maternal blood: quantity and quality of fetal cells in enriched populations.
Isolation of fetal DNA from nucleated erythrocytes
in maternal blood.
In addition, nucleated erythrocytes
express several antigens, such as the transferrin receptor expressed on rapidly dividing cells, that might be useful targets for enriching samples of maternal blood.