NR3C1(redirected from nuclear receptor subfamily 3 group C member 1 variant NS-1)
NR3C1A gene on chromosome 5q31.3 that encodes a glucocorticoid receptor, which acts as either a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, or as a regulator of other transcription factors.
NR3C1 mutation are associated with generalised glucocorticoid resistance.
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