nuclear export signal


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nuclear export signal

One or more clusters of receptor-specific basic amino acids that are present on macromolecules (proteins and ribonucleioproteins) and tag them for transportation across the nuclear pore complex. The signal for exporting cellular RNAs is uncertain, and requires completion of post-translational processing events.
References in periodicals archive ?
In an experiment with yeast cells, Weis and his colleagues created an artificial protein with three components: a nuclear localization signal, Rev's nuclear export signal, and a fluorescent protein.
Depending upon the movement of macromolecules from cytoplasm to nucleus or nucleus to cytoplasm, these karyopherins target the substrates that contain nuclear localization signal (NLS) or nuclear export signals (NES).

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