nuclear antigen


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nuclear antigen

An antigen present in the cells of patients with certain types of connective tissue disorders. Corticosteroids can be very helpful in treating patients with high concentrations of nuclear antigen.
See also: antigen
References in periodicals archive ?
EBV specific antibodies include Viral Capsid Antigen (VCA IgM) and Nuclear Antigen (EBNA IgG).
They later looked at various markers of cell growth, including proliferating cell nuclear antigen (PCNA), one of the best-characterized markers of cell growth.
The commercial monoclonal antibody therefore most often used for this purpose is directed against the C-terminus of LNA1 (latency-associated nuclear antigen or LANA1) encoded by ORF-73.
Tissue sections were stained with periodic acid-Schiff's reagent and immunostained to detect proliferating cell nuclear antigen (PCNA, a marker of proliferating cells), followed by image analysis of uterine caruncular areas.
Fourth is an antibody to EBV nuclear antigen (EBNA).
Additionally, numerous studies involving proliferating cell nuclear antigen (PCNA) and the bcl-2 protein have been conducted to determine the processes related to cell proliferation and, consequently, the susceptibility of some tumors to malignant transformation (Ohtake et al.
We performed an immunohistochemical analysis of the expression of proliferating cell nuclear antigen (PCNA) and bcl-2 protein in 15 patients with laryngeal BSCC and 15 stage- and site- matched controls with typical laryngeal SCC.
At her primary care physician's office, she had serologic testing done for EBV viral capsid antigen (VCA), early antigen (EA), and nuclear antigen (EBNA).
Tests for antibodies to Epstein-Barr viral capsid antigen (EBVCA) or Epstein-Barr nuclear antigen (EBNA) are the most sensitive, are highly specific, and are also the most expensive for diagnosing infectious mononucleosis (strength of recommendation [SOR]: C, based on validating cohort study).
They also found that fibroid-cell cultures treated with CDB-2914 had lower concentrations of two proteins: proliferating cell nuclear antigen (PCNA) and Bcl-2.

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