notochord


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

notochord

 [no´to-kord]
a cylindrical cord of cells on the dorsal aspect of an embryo, marking its longitudinal axis; the common factor of all chordates. It is the center of development of the axial skeleton.

no·to·chord

(nō'tō-kōrd),
1. In primitive vertebrates, the primary axial supporting structure of the body, derived from the notochordal or head process of the early embryo; an important organizer for determining the final form of the nervous system and related structures.
2. In embryos, the axial fibrocellular cord about which the vertebral primordia develop; vestiges of it persist in the adult as the nuclei pulposi of the intervertebral discs. Synonym(s): chorda dorsalis
[G. nōtos, back, + chordē, cord, string]

notochord

(nō′tə-kôrd′)
n.
A flexible rodlike structure that is present in the embryos of all chordates and in the adult forms of certain groups, such as the lancelets and hagfishes. The notochord develops into the spinal column in most vertebrates.

no′to·chord′al adj.

no·to·chord

(nō'tō-kōrd)
1. In primitive vertebrates, the primary axial supporting structure of the body, derived from the notochordal or head process of the early embryo; an important organizer for determining the final form of the nervous system and related structures.
2. In embryos, the axial fibrocellular cord about which the vertebral primordia develop; vestiges of it persist in the adult as the nuclei pulposi of the intervertebral discs.
[G. nōtos, back, + chordē, cord, string]

notochord

A rod-like structure, present in early development, derived from the MESODERM and giving rise to the spine. In the adult, the notochord is represented by the pulpy centres (nucleus pulposus) of the intervertebral discs.

notochord

the longitudinal axial support (skeleton) of the embryos of all chordates, which lies ventral to the nerve cord and dorsal to the alimentary canal. Remnants of the notochord usually remain in the adult between the vertebrae, which come to surround it.

no·to·chord

(nō'tō-kōrd)
In embryos, the axial fibrocellular cord about which vertebral primordia develop; vestiges persist in the adult as the nuclei pulposi of the intervertebral discs.
[G. nōtos, back, + chordē, cord, string]
References in periodicals archive ?
Once the scientists had the notochord cells, they used a similar chemical exposure process to develop those into NP-type cells.
In chick embryos, it has been shown that the adjacent notochord allows the Pdx1 expression, thereby inducing the budding of the dorsal pancreas by deactivating the sonic hedgehog expression coming from the dorsal foregut epithelium (36).
Apart from the 3 mutants with only spina bifida (Fgfr1, Shp2, and Gcm1) which have 2 neural tubes with one notochord, 2 other mutants with spinal defect but no spina bifida share the same predicament.
Tessier-Lavigne, "Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog," Cell, vol.
Parichy, "Critical early roles for col27a1a and col27a1b in zebrafish notochord morphogenesis, vertebral mineralization and postembryonic axial growth," PLoS ONE, vol.
Keywords: Chordoma, Notochord, Cervical spine, En bloc resection, C3-C4 spine.
ZF embryos exposed to ziram early in development resulted in marked notochord malformations (see Figure S2b,c) similarly to other dithiocarbamates (Haendel et al.
The notochord of hagfish Myxine glutinosa: visco-elastic properties and mechanical functions during steady swimming.
A long, thin tube running down the creature's back was not part of the gut, as some scientists had suggested, but a notochord, a structural hallmark of vertebrates.
According to location, polymelia is named as notomelia, cephalomelia, thoracomelia and dipygus or pygomelia where the extra limbs are attached in region of embryonic notochord on head, on thorax to margin of scapula of normal limb and to pelvis respectively (Denholm, 2011).
The lower vertebral column formation is also less well organized and forms from a mass of cells composed of notochord, mesenchyme, and neural tissue which divide to form sacral and coccygeal somites.