notexin

notexin

A phospholipase enzyme from snake venom that attacks muscle cells and motor nerve terminals. It has been proposed for the treatment of upper lid droop (blepharoptosis) in mitochondrial myopathy, to encourage the proliferation of satellite muscle cells, which contain mostly normal mitochondria.
References in periodicals archive ?
The soleus muscle consisted of entirely new myofibers after 5 days of notexin treatment, later 98% of them expressed slow myosin (Whalen et al.