Upon completion of the test, participants rested in a seated position for 3 min in the environmental condition for that testing day, before exiting the environmental chamber and remaining under normoxic
The cells incubated under normoxic
conditions were homogenously plated into the channels of the chips.
We harvested EMPcontrol and EMPhypoxia from the culture medium of HUVECs that were, respectively, exposed to in normoxic
and hypoxic conditions for 12 h.
Cells placed under normoxic
conditions were maintained according to the parameters as described in preceding paragraphs, whereas, for subjecting to hypoxia stress, the HEK 293 cells were retained in a low oxygen environment (1% [O.sub.2], 5% C[O.sub.2], and 94.5% [N.sub.2]) for 24 h in a Galaxy 48R incubator (New Brunswick).
The most important concern may however be the lack of a clear cutoff value to discriminate between "hypoxic" and "normoxic
" (i.e., "less hypoxic") tumors in these studies.
As shown in Figures 1(a) and 1(b), H9C2 cells exposed to HG stimulation exhibited decreased cell viability and increased LDH release as compared with LG group in normoxic
conditions, and these alterations were further increased by H/R insult as compared with those in the corresponding normoxic
groups, indicating that HG-treated H9C2 cells are more vulnerable to H/R injury.
All subjects performed two trials: (a) normobaric normoxic
exercise (room air; equivalent altitude to 400 m) and (b) normobaric hypoxic exercise (fraction of inspired oxygen: Fi[O.sub.2] = 0.13).
Groups of male and female Wt and STAT5-/- mice were exposed to hypoxia (10% hypobaric oxygen) for 4 weeks or kept under normoxic
conditions, and the development of PAH was first evaluated as previously reported (RVSP, ratio of RV/LV + S weights, increased muscularization of vessels, and increased arterial wall thickness) .
For reoxygenation, following hypoxic conditions, the medium was replaced with fresh medium and the cells were kept in normoxic
Recent data from a study using pharmacological blockade of the sympathetic and parasympathetic nervous system  suggest that even though sympathetic nervous system activity increases as compared to normoxic
state, parasympathetic withdrawal rather than sympathetic activation seems to be the cause of the increase in heart rate observed in healthy humans subjected to hyperbaric hypoxia.
Long-term submergence at 3AdegC of the turtle, Chrysemys Picta Bellii, in normoxic
and severely hypoxic water: I.
Polymer gels were manufactured to solve the problem of oxygen contamination by adding oxygen scavenger.27