With smaller numbers of samples, recent studies on sequence diversity in genes encoding the normocyte
binding protein (Pknbpxa) (10) and the Duffy binding protein (PkDBP) (30), as well as the 18S rRNA gene and the mitochondrial Cox1 gene, have suggested that parasites in peninsular Malaysia had probably diverged from those in Malaysian Borneo.
G6PD deficiency is the most common enzyme deficiency in humans and affects over400 million people worldwide.4 The glutathione pathway is paramount to antioxidant defense and G6PD-deficient cells do not cope well with oxidative damage.5 Normal values of G6PD 6-phosphogluconate dehydrogenase (6PGD) and glutathione reductase (GR) have been determined in normocytes
reticulocytes newborn cord erythrocytes and leukocytes.6 Iron is a vital mineral that is widely encountered in biological systems.
In addition to being larger, they also have an altered pattern of chromatin deposits in the nucleus which helps distinguish them from normocytes
. Hemoglobin increases in proportion to the size of the cell.
If the values are normal, the cells are simply normocytes