In addition to demographic information, we reviewed patient records for the specific type of operative procedure that was performed, patients' serum calcium levels, LOS, early detection of postoperative normocalcemia, the type of treatment, and follow-up.
The combination of an absolute serum calcium level at 4 to 6 hours and the change in level from the preoperative value was not an accurate predictor of normocalcemia (figure 2).
All had normocalcemia
, and 85% had single-gland disease at the time of surgery.
Cinacalcet hydrochloride maintains long-term normocalcemia
in patients with primary hyperparathyroidism.
Because aminobisphosphonates rapidly block bone resorption, they can lead to hypocalcemia followed by a secondary hyperparathyroid response to restore normocalcemia
4) Our patient presented with diffuse splenic calcification with normocalcemia
before undergoing chemotherapy.
In patients with renal failure, our data showed that not only was the qPTH successful in predicting postoperative normocalcemia
, but assay levels dropped appropriately 5 minutes after subtotal resection, which is consistent with results for most patients with uniglandular disease.
Surgical approaches to the treatment of patients with primary nonsyndromal hyperparathyroidism are designed to find and remove the abnormal parathyroid tissue and re-establish normocalcemia
The patient will likely return with recurrent hypercalcemia, which may be identified in the immediate postoperative period or more likely within 5 years (often, normocalcemia
Cure of all patients was confirmed by their 1-year outcome of normocalcemia
Harness et al" has defined the criteria for the diagnosis of multiple parathyroid adenomas as (1) more than 1 and fewer than 4 enlarged parathyroid glands at operation, (2) operative finding of at least one normal parathyroid gland, (3) evidence of neither multiple endocrine neoplasia nor familial hyperparathyroidism, and (4) permanent normocalcemia
after resection of the enlarged parathyroid glands.
The 5-min half-life of intact PTH allows it to serve as a practical intraoperative marker, and previous studies suggested that a 50% decrease in PTH values from the presurgical value after removal of the diseased gland(s) reliably predicts postoperative normocalcemia