normoblast


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

normoblast

 [nor´mo-blast]
a nucleated precursor cell in the erythrocytic series, specifically one in a normal course of erythrocyte maturation, as opposed to a megaloblast. The four developmental stages of the series are called pronormoblasts or proerythroblasts, basophilic normoblasts or erythroblasts, polychromatophilic (or polychromatic) normoblasts or erythroblasts, and orthochromatic normoblasts or erythroblasts. adj., adj normoblas´tic.

nor·mo·blast

(nōr'mō-blast),
A nucleated red blood cell, the immediate precursor of a normal erythrocyte in humans. Its four stages of development are: 1) pronormoblast, 2) basophilic normoblast, 3) polychromatic normoblast, and 4) orthochromatic normoblast See: erythroblast.
[normo- + G. blastos, sprout, germ]

nor·mo·blast

(nōr'mō-blast)
A nucleated red blood cell, the immediate precursor of a normal erythrocyte in humans. Its four stages of development are: 1) pronormoblast, 2) basophilic normoblast, 3) polychromatic normoblast, and 4) orthochromatic normoblast.
See also: erythroblast
[normo- + G. blastos, sprout, germ]

normoblast

A nucleated red blood cell precursor showing the features of normal red cell development, as distinct from those of the MEGALOBLAST.

nor·mo·blast

(nōr'mō-blast)
A nucleated red blood cell, the immediate precursor of a normal erythrocyte in humans.
[normo- + G. blastos, sprout, germ]
References in periodicals archive ?
Few normoblasts were seen in HbSS, but seen occasionally in HbSA.
Clusters of normoblasts (extramedullary hematopoiesis) are commonly seen, as in fetal liver.
Cellularity : Low cellularity M: E ratio : Increased 7:1 Erythroid Series : Erythroid series hypoplasia, few colonies of normoblasts Myeloid Series : Few granulocytes, few myelocytes, few metamyelocytes.
The bone marrow aspiration revealed bi- and tri-nucleated normoblasts indicating erythroid hyperactivity and dyserythropoiesis with increased histiocytes without any evidence of hemophagocytosis.
Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.
The peripheral blood smear films for blood cells and parasites had significant polychromasia and anisocytosis and presence of normoblasts but there were no plasmodia and microfilaria.
The possible explanations of anemia are intramedullary destruction of normoblasts with Rh antibodies and low erythropoietin levels due to suppression of the bone marrow by IUT (1), (6), (9).
The differential on 500 cells revealed the following values: 0.01 myeloblasts; 0.01 promyelocytes; 0.15 myelocytes; 0.28 metamyelocytes; 0.40 granulocytes; 0.02 eosinophils; 0.01 basophils; 0.01 lymphocytes; 0.01 monocytes; and 0.09 normoblasts. The myeloid-erythroid ratio was 9.8:1.
The multivariate statistic is far more sensitive than histogram analysis to the presence of circulating normoblasts, for instance, and has flagged such specimens almost unerringly.
All areas with terminal villous capillaries were examined at 40x magnification until either 3 fields containing at least 2 unequivocal normoblasts in a single terminal villus were seen (increased NRBC) or the scan was completed.