low-tension glaucoma

(redirected from normal-tension glaucoma)

low-ten·sion glau·co·ma

optic nerve atrophy and excavation with typical field defects of glaucoma but without abnormal increase in intraocular pressure.

low-ten·sion glau·co·ma

(lōw-ten'shŭn glaw-kō'mă)
Optic nerve atrophy and excavation with typical field defects of glaucoma but without abnormal increase in intraocular pressure.
Synonym(s): normal-tension glaucoma.

low-tension glaucoma

A type of glaucoma in which intraocular pressures are normal (less than 22 mm Hg).
See also: glaucoma
References in periodicals archive ?
Postural response of intraocular pressure and visual field damage in patients with untreated normal-tension glaucoma. J Glaucoma.
Psychological characteristics of patients with normal-tension glaucoma. Graefes Arch Clin Exp Ophthalmol 1999;237:753-7.
Nocturnal measurements of intraocular pressure in patients with normal-tension glaucoma and sleep apnea syndrome.
Oshika, "Relationship of progression of visual field damage to postural changes in intraocular pressure in patients with normal-tension glaucoma," Ophthalmology, vol.
Risk factors for progression of visual field abnormalities in normal-tension glaucoma. Am J Ophthalmol.
(3,4,6) It has been shown that with lower IOP and in cases of normal-tension glaucoma (NTG), there is less incidence of SVP and a greater pressure needs to be applied to the globe in order to induce SVP; this equates to a greater difference in IOP and CRV pressure and implies that local vessel haemodynamics are involved in the glaucoma process.
Some people have low-tension or normal-tension glaucoma, where optic nerve damage occurs even when the IOP is in the normal range (12-22 millimeters of mercury).
[6] Previous studies reported that about one-third of patients with glaucoma without elevated IOP are affected with normal-tension glaucoma. [7] About 12% of all cases of blindness worldwide are due to POAG.
However, in a significant proportion of patients designated normal-tension glaucoma (NTG), the disease occurs in spite of normal IOP and thus other risk factors must also be involved in the optic neuropathy of POAG [6].
Correlation of age and intraocular pressure with visual field damage in patients with normal-tension glaucoma. Nihon Ganka Gakki Zasshi 2008; 112:371-5.
[7] Nitta E, Hirooka K, Tenkumo K, Fujita T, Nishiyama A, Nakamura T, et al Aldosterone: A mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma. Cell Death Dis 2013;4:e711.
In fact, probucol protects against glutamate-induced cytotoxicity in a neuronal cell line [72] and, intriguingly, glutamate toxicity is one of the main pathogenic mechanisms of normal-tension glaucoma [73-76].