All received a daily OC (Ortho-Cyclen; 250 meg norgestimate
, 35 meg ethinyl estradiol).
The company added that the Norgestimate
and Ethinyl Estradiol Tablets USP are the generic version of Janssen's Ortho Tri-Cyclen Lo Tablets.
After accounting for smoking, obesity, a wide range of other health conditions, alcohol consumption, polycystic ovary syndrome and recent infections, surgeries, leg/hip fractures, and hospital admission, the researchers calculated an increased odds ratio for each hormone: desogestrel (4.28), cyproterone (4.27), drospirenone (4.12), gestodene (3.64), levonorgestrel (2.38), norgestimate
(2.53), and norethisterone (2.56).
Ethinyl estradiol and norgestimate
: Combination of estrogen and progestin.
Existing progestogen compounds can be classified as first- (e.g., norethisterone, norethindrone, ethynodiol diacetate, and lynestrenol), second- (levonorgestrel and norgestrel), and third-generation (desogestrel, gestodene, and norgestimate
Combined OCPs administered to the patients included the following: desogestrel 0.15 mg/ethinyl estradiol 0.03 mg, desogestrel 0.15 mg/ethinyl estradiol 0.02 mg, desogestrel 0.15 mg/ethinyl estradiol 0.03 mg, ethynodiol diacetate 1 mg/ethinyl estradiol 0.035 mg, drospirenone 3 mg/ethinyl estradiol 0.03 mg, norgestimate
0.25 mg/ethinyl estradiol 0.035 mg and norethindrone 1 mg/ethinyl estradiol 0.05 mg.
Talk to your health care professional about a pill formulation with progestins that do not have an androgen effect and which are known to elevate SHBG, such as norgestimate
, drospirenone or desogestrel.
As well as this targeted review, the European Medicines Agency (EMA) is currently carrying out an overall review of combined contraceptives containing the following progestatives: chlormadinone, desogestrel, dienogest, drospirenone, etonogestrel, gestodene, nomegestrol, norelgestromine and norgestimate
. PRAC's recommandations are expected for July.
a review of combined contraceptives containing chlormadinone, desogestrel, dienogest, drospirenone, etonogestrel, gestodene, nomegestrol, norelgestromin and norgestimate
In addition, primary care physicians prescribed the oral contraceptive combination norgestimate
/ ethinyl estradiol for 8.6% of acne visits, according to the analysis.
(1995) Effect of two oral contraceptives containing ethinylestradiol and gestodene or norgestimate
upon androgen parameters and serum binding proteins.