norethisterone


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norethisterone

A PROGESTOGEN drug used to treat excessive menstrual bleeding, painful menstruation, ENDOMETRIOSIS and metastatic breast cancer. The drug is on the WHO official list. Brand names are Primolut N and Utovlan. The drug is also widely used in combination with an oestrogen as an oral contraceptive. It is formulated with ETHINYLOESTRADIOL (ethinylestradiol) under such brand names as Binovum, Brevinor, Loestrin 20, Norinyl-1, Otho-Novin 1/50, Ovysmen, Synphase and Trinovum; and with oestradiol (estradiol) valerate under the brand names Climagest and Climesse.

norethisterone, norethindrone

a progestin.
References in periodicals archive ?
Conclusion: The levonorgestrel intrauterine system was better than norethisterone with marked clinical benefit of profound reduction in menstrual blood loss.
Overexpression of progesterone receptor membrane component 1: possible mechanism for increased breast cancer risk with norethisterone in hormone therapy.
DMPA (63%) and norethisterone enantate (21%) are the most commonly used injectable contraceptives (3).
Norethisterone acetate (tablets); marketed as Nor--Q-D and Aygestin.
A: Your GP may be able to prescribe medication and will advise you when to take norethisterone and for how long.
Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a ran domized controlled trial.
Group I: Transdermal estradiol (Climara 3,9 mg transdermal patch applied every week; Schering, Istanbul, Turkey) and oral norethisterone acetate (NETA) (Primolut-N tb 10 mg/day, last 12 days of every month; Bayer, Istanbul, Turkey) n=60;
Djerassi, now 88 years old, was one of three researchers whose formulation of the synthetic progestagen Norethisterone marked a key step in the creation of the first oral contraceptive pill.
Progestins such as norethisterone acetate may be administered with or without addition of low doses of oestrogens to safely and effectively extend GnRHa therapy while minimizing side effects.
Norethisterone has also been approved as a permitted suppressant, and there is research taking place into a threshold level for testererone - which has been used as a mascuslinising steroid.
Fifty-six premenopausal women (mean age, 47 years) with abnormal bleeding due to non-atypical endometrial hyperplasia were randomly assigned to receive, in double-blind fashion, genistein (as genistein aglycone, 54 mg/day), norethisterone acetate (a progestin, 10 mg/day on days 16-25 of the menstrual cycle), or placebo for six months.
The anti- doping disciplinary panel headed by retired judge Dinesh Dayal, however, concluded on Wednesday that the presence of the banned substance in her sample was due to the intake of norethisterone, which is not prohibited by WADA.