nonulcer dyspepsia

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impairment of the power or function of digestion; usually applied to epigastric discomfort after meals. adj., adj dyspep´tic.
acid dyspepsia dyspepsia associated with excessive acidity of the stomach.
nonulcer dyspepsia dyspepsia in which the symptoms resemble those of peptic ulcer, although no ulcer can be detected. Because many patients with nonulcer dyspepsia have a Helicobacter pylori infection, H. pylori has been suggested as a cause. This has not been proven, however, and many patients still have dyspepsia after antibiotic treatment.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

functional dyspepsia

Dyspepsia without endoscopic or histologic evidence of an organic disease to explain the symptoms.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

nonulcer dyspepsia

Upper abdominal discomfort, often chronic, in which endoscopy reveals nondiagnostic, or normal, findings.
See also: dyspepsia
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Therapy for Helicobacter pylori in patients with nonulcer dyspepsia. A meta-analysis of randomized, controlled trials.
In addition, a prospective cohort study of Japanese patients with nonulcer dyspepsia found that 4.7% of patients infected with H pylori developed gastric cancer after 10 years.
Using PubMed (, we entered the search term "nonulcer dyspepsia AND helicobacter pylori."
However, most patients with dyspepsia do not have one of these conditions, and are considered to have functional or nonulcer dyspepsia. The diagnosis and management of adults with GERD was recently described in detail.[2] Therefore, this paper reviews the treatment of undifferentiated dyspepsia, gastric ulcer caused by nonsteroidal anti-inflammatory drugs (NSAIDs), peptic ulcer disease not associated with NSAID use, and nonulcer dyspepsia (dyspepsia in a patient who has no evidence of ulcer or GERD on endoscopy).
Findings from a prospective long-term study of 1,526 consecutive patients presenting with either active duodenal or gastric ulcers, gastric hyperplastic polyps, or nonulcer dyspepsia showed that 1,246 were infected with H.
* POPULATION STUDIED The authors combined the results of 10 studies of therapy of 1747 patients with nonulcer dyspepsia and documented H pylori infection.
About 30% of patients with nonulcer dyspepsia have a concurrent H.
Is Helicobacter pylori associated with nonulcer dyspepsia and will eradication improve symptoms?
Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia. N Engl J Med 1999; 341:1106-11.
Patients with nonulcer dyspepsia were treated symptomatically.
Clinical question Is Helicobacter pylori eradication an effective treatment for patients with functional or nonulcer dyspepsia?
Clinical question Does eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia improve symptoms?