nonsteroidal antiinflammatory drug


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non·ste·roi·dal an·ti·in·flam·ma·to·ry drug

(NSAID) ( non'ster-oy'dăl an'tī-in-flam'ă-tŏr-ē drŭg)
Any one of a group of pharmacotherapeutic agents exerting antiinflammatory (and also usually analgesic and antipyretic) actions (e.g., aspirin, diclofenac, ibuprofen, and naproxen). A contrast is made with steroidal compounds (e.g., hydrocortisone or prednisone) exerting antiinflammatory activity.

Patient discussion about nonsteroidal antiinflammatory drug

Q. Is there any good source for heel pain relief, besides NSAIDs? My heel pain is most severe at night when I sleep. It's as if the way I position my feet worsen the condition, but I'm at a loss to know how to position my feet. During the day my heels feel so but don't typically bother me.

A. I have found that keeping my feet flexed (the position they are in when standing) helps ease the pain of plantar facitis. I also don't let my feet get cold(wear socks)and keep heavy blankets and quilts off the feet. Placing a box under the covers at the foot of the bed will help keep the blankets up. Do try the exercises recommended on the above web sites. It usually resolves in about 6 months. Best wishes!

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References in periodicals archive ?
The cost-effectiveness of misoprostol for nonsteroidal antiinflammatory drug associated adverse gastrointestinal events.
Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarction.
It also alerts you to take other steps to protect your kidneys, such as staying well hydrated and steering clear of toxic substances that can hasten kidney-function decline--namely, nonsteroidal antiinflammatory drugs, like ibuprofen (Advil[R], Motrin[R]) and naproxen (Aleve[R]), and contrast agents used in certain imaging studies.
Szczepanski et al., "Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprozole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group," The New England Journal of Medicine, vol.
Conventional nonsteroidal antiinflammatory drugs (NSAIDs) and recently developed COX-2-specific inhibitors have shown considerable promise in prevention of some forms of human cancer; however, its application is limited due to severe toxic side effects on normal cells.
Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N Engl J Med 1999 Jun; 340(24):1888-1899.
Hypersensitivity Reactions to Nonsteroidal AntiInflammatory Drugs: An Update.
Renal side effects of nonsteroidal antiinflammatory drugs: Clinical Relevance.
Patients with fibromyalgia often use nutritional supplements as well as over-the-counter analgesics--including ibuprofen and nonsteroidal antiinflammatory drugs (NSAIDs), and acetaminophen--and usually only experience modest pain relief.
Hawkey CJ, Cullen DJ, Greenwood DC, Wilson JV, Logan RF 1997 Prescribing of nonsteroidal antiinflammatory drugs in general practice: determinants and consequences Alimentary Pharmacology & Therapeutics 11 293-298
"Analytic studies on aspirin or non-aspirin nonsteroidal antiinflammatory drugs (NSAIDs) and the risk of diabetes" outside of clinical trials are limited, write Dr.

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