nonsteroidal antiinflammatory drug


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nonsteroidal antiinflammatory drug (NSAID)

[-stir′oidəl]
any of a group of drugs having antipyretic, analgesic, and antiinflammatory effects. They counteract or reduce inflammation by inhibiting cyclooxygenase, the enzyme responsible for prostaglandin synthesis. NSAIDs may be indicated in the treatment of mild-to-moderate pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylosis, gouty arthritis, fever, nonrheumatic inflammation, and dysmenorrhea. Classic examples include aspirin, ibuprofen, and ketoprofen. Newer drugs such as celecoxib, refecoxib, and valdecoxib selectively block only the inductible form of cyclooxygenase (COX-2), the form of the enzyme that appears in cells at sites of inflammation, and tend to have fewer side effects.

non·ste·roi·dal an·ti·in·flam·ma·to·ry drug

(NSAID) ( non'ster-oy'dăl an'tī-in-flam'ă-tŏr-ē drŭg)
Any one of a group of pharmacotherapeutic agents exerting antiinflammatory (and also usually analgesic and antipyretic) actions (e.g., aspirin, diclofenac, ibuprofen, and naproxen). A contrast is made with steroidal compounds (e.g., hydrocortisone or prednisone) exerting antiinflammatory activity.

Patient discussion about nonsteroidal antiinflammatory drug

Q. Is there any good source for heel pain relief, besides NSAIDs? My heel pain is most severe at night when I sleep. It's as if the way I position my feet worsen the condition, but I'm at a loss to know how to position my feet. During the day my heels feel so but don't typically bother me.

A. I have found that keeping my feet flexed (the position they are in when standing) helps ease the pain of plantar facitis. I also don't let my feet get cold(wear socks)and keep heavy blankets and quilts off the feet. Placing a box under the covers at the foot of the bed will help keep the blankets up. Do try the exercises recommended on the above web sites. It usually resolves in about 6 months. Best wishes!

More discussions about nonsteroidal antiinflammatory drug
References in periodicals archive ?
Nonsteroidal antiinflammatory drug use and acute myocardial infarction.
The cost-effectiveness of misoprostol for nonsteroidal antiinflammatory drug associated adverse gastrointestinal events.
Non-selective nonsteroidal antiinflammatory drugs and cardiovascular events: is aldosterone the silent partner in crime?
Effect of ranitidine on gastroduodenal mucosal damage induced by nonsteroidal antiinflammatory drugs.
Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugs.
Could nonsteroidal antiinflammatory drugs (NSAIDs) enhance the progression of bacterial infections to toxic shock syndrome?
Assessing the relationship between the use of nonsteroidal antiinflammatory drugs and necrotizing fasciitis caused by group A streptococcus.
Nonsteroidal antiinflammatory drugs, acetaminophen and the risk of cardiovascular events.
Vad, glucosamine and chondroitin may have antiinflammatory effects that help relieve knee osteoarthritis pain, although these effects are somewhat different from those of Celebrex or other nonsteroidal antiinflammatory drugs (NSAIDs).
In the 30 days before hospital admission she had not received medications other than nonsteroidal antiinflammatory drugs for 5 days.
And where use of nonsteroidal antiinflammatory drugs was associated with significantly more endoscopic findings in both the [H.
The warning was a precondition to FDA's OTC marketing approval of three recently introduced nonsteroidal antiinflammatory drugs (NSAIDs): ALEVE, ORUDIS KT (also marketed by American Home Products), and ACTRON.

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