nonspecific protein

non·spe·cif·ic pro·tein

a protein substance that elicits a response not mediated by specific antigen-antibody reaction.

non·spe·cif·ic pro·tein

(non'spĕ-sif'ik prō'tēn)
A protein substance that elicits a response not mediated by specific antigen-antibody reaction.
References in periodicals archive ?
The authors therefore concluded that coatings based on polyurethane resins modified with zwitterionic groups have the potential to provide effective nonspecific protein resistance.
Methods used to quantitate albumin in human samples have included salt fractionation, immunochemistry, protein electrophoresis (EPH), and the use of nonspecific protein binding dyes.
Optimization of capture ligand selection and immobilization, assay calibration, and assay performance (determination of sample incubation times, reduction of cross-reactivity between assays, and nonspecific protein binding) are important development components for both planar and suspension multiplex formats.
Low native autofluorescence showcases better assay signal-to-noise performance and greater sensitivity, according to the company, and there is no nonspecific protein binding, making the untreated COP plate ideal for highly sensitive enzyme-based assays.
This indicated that V, a nonspecific protein tyrosine phosphatase inhibitor, may also activate other signaling proteins that counteract vasoconstriction.
MUSTANG Q membrane using a proprietary polyethersulfone formulation provides low, nonspecific protein absorption, which helps enhance performance and efficiency for specific chromatography processes, such as the purification of antisense oligonucleotides.
The OptArray offers low background noise and lower nonspecific protein binding than most other microarray coatings.
A single-value correction factor is often used to correct for nonspecific protein interference in Jaffe assays, but this approach does not take into account differences in plasma albumin concentrations among samples.
In my opinion, however, they may also be explained by the use of nonspecific protein binding assays because UFC values in previous investigations (3-5) were higher than UFC amounts measured by more-specific methods such as chromatography/RIA (9,10) and HPLC (11-13).
Affinity chromatography and onbead digestion were performed in 500-[micro]L siliconized microtubes (Fisher Scientific) to minimize nonspecific protein loss.
Whole cells can be detected and media samples rich in nonspecific proteins and fatty molecules may be tested with no performance degradation.

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