nonshivering thermogenesis


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nonshivering thermogenesis

thermogenesis resulting from the effects of the sympathetic nervous system neurotransmitters, epinephrine, and norepinephrine, acting to increase the cellular metabolic rate in skeletal muscle and other tissues, thereby increasing heat production. In a specialized form of adipose tissue, brown fat, the effect of the sympathetic neurotransmitters is to increase the rate of uncoupled oxidative phosphorylation by the mitochondria, which results in heat production without formation of adenosine 5'-triphosphate.

non·shiv·er·ing ther·mo·gen·e·sis

(non-shiv'ĕr-ing thěr'mō-jen'ĕ-sis)
Thermogenesis resulting from the effects of the sympathetic nervous system neurotransmitters, epinephrine and norepinephrine, acting to increase the cellular metabolic rate in skeletal muscle and other tissues, thereby increasing heat production. In a specialized form of adipose tissue, brown fat, the effect of the sympathetic neurotransmitters is to increase the rate of uncoupled oxidative phosphorylation by the mitochondria, which results in heat production without formation of adenosine triphosphate.
References in periodicals archive ?
Nonshivering thermogenesis (NST) was induced by subcutaneous injection of norepinephrine (NE) (Shanghai Harvest Pharmaceutical Co., Ltd.) and measured at 25AdegC.
Electrical stimulation of the posterior and ventromedial hypothalamic nuclei causes specific activation of shivering and nonshivering thermogenesis. Can J Physiol Pharmacol.
Adaptive evolution of the uncoupling protein 1 gene contributed to the acquisition of novel nonshivering thermogenesis in ancestral eutherian mammals.
Facultative thermogenesis or nonshivering thermogenesis is an increase in BMR during periods of exposure to cold or prolonged exposure to caloric excess.
Thermoregulatory responses to photoperiod by Kangaroo rats (Dipodomys ordii): Influence of night lighting on nonshivering thermogenesis and resting metabolism.
Nonshivering thermogenesis (NST) through brown fat metabolism is the primary heat producing mechanism in the newborn.
However, endotherms require appropriate responses and efficient thermoregulatory mechanisms (Klingenspor et al., 2000) to regulate body mass and thermogenic capacity (nonshivering thermogenesis, NST) to cope with winter-like conditions (Chi and Wang, 2011; Concannon et al., 2001; Krol and Speakman, 2007; Li and Wang, 2005; Zhang et al., 2011; Zhang and Wang, 2007; Zhu et al., 2010; Nieminen and Hyvarinen, 2000).