nonsecretory myeloma


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non·se·cre·to·ry my·e·lo·ma

multiple myeloma in which there is no detectable paraproteinemia or paraproteinuria.

nonsecretory myeloma

Multiple myeloma is which there is infiltration of the bone marrow by abnormal plasma cells, hypercalcemia, anemia, renal failure, or pathological bone fractures, but in which a monoclonal protein cannot be detected in either the urine or the blood.
See also: myeloma
References in periodicals archive ?
Information about serum FLC measurement in nonsecretory myeloma, monoclonal light chain diseases, and reference populations is reported in the literature (1-5,7), but there is limited data about FLCs in renal disease, monoclonal gammopathy of undetermined significance (MGUS), and myeloma patients after autologous stem cell transplants.
The Freelite assay is a sensitive automated immunoassay for [kappa] and [lambda] FLCs in serum (3) and has been useful for the diagnosis and monitoring of patients with nonsecretory myeloma (4).
The clinical application of serum free light chain measurements was particularly apparent for detecting and monitoring patients with nonsecretory myeloma and primary amyloidosis.