There was one participant with an undetectable HIV viral load, consistent with her clinical status as a long-term nonprogressor
In addition, serum Sema4D levels were significantly higher in the radiographic progressors than those in the nonprogressor
group (Figure 3).
Lake, "Hepatitis B reactivation in a long-term nonprogressor
due to nivolumab therapy," AIDS, vol.
Wang et al., "Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor
and in CMV infection," Blood, vol.
In clinical studies comparing HIV-1 progressor and nonprogressor
patients, an R77Q variation was correlated with slower disease progression (long-term nonprogression) .
First demonstration of a lack of viral sequence evolution in a nonprogressor
, defining replication-incompetent HIV-1 infection.
(4-5) The classic example is the Sydney Blood Bank Cohort, where a group of 8 recipients of blood products were infected with a nef/LTR-deleted strain of HIV from a long-term nonprogressor
(reviewed in Zaunders et al (6)).
(34.) Braibant M, Xie J, Samri A, Agut H, Autran B, Barin E Disease progression due to dual infection in an HLA-B57- positive asymptomatic long-term nonprogressor
infected with a nef-defective HIV-1 strain.
For years I was a "nonprogressor
." (An HIV+ person who shows no signs or symptoms of disease progression for over 12 years is called a nonprogressor
or a long-term nonprogressor
, LTNP.) But as my CD4 cells drifted down to 400, I got tired.
Combined genotypes of CCR5, CCR2, SDF1, and HLA genes can predict the long-term nonprogressor
status in human immunodeficiency virus-1-infected individuals.
In addition to this, there is evidence that in certain cases individuals known as long-term nonprogressor
(LTNP), infected with HIV, remain asymptomatic without antiretroviral therapy (ART) in their life time due to the slow or arrested evolution of HIV .
Increased pDCs have been associated with nonprogressor