nonoxynol-9


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Related to nonoxynol-9: spermicide

nonoxynol-9

(nŏn-ŏk′sə-nôl′nīn′, -nŏl′-, -nōl′-)
n.
A spermicide widely used in contraceptive creams, foams, and lubricants.

nonoxynol-9

A SURFACTANT spermicidal drug intended for use in conjunction with barrier contraceptives. It is available as a foam, pessary, gel, or cream. Brand names are Delfen, Double Check, Ortho-Forms, Duragel, Gynol II and Ortho-Creme.
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References in periodicals archive ?
Rosenberg stated that this unique combination could have important implications for global world health, in part because, according to the World Health Organization and FDA-mandated labeling requirements in effect since December 2007, the currently marketed nonoxynol-9 vaginal gel may actually increase the risk of acquisition of HIV in some circumstances.
CRO Health Decisions, Evofem Lock Database in Largest Contraceptive Trial of Its Type
A similar effect was seen in Nonoxynol-9 treated Sertoli cells which served as the positive controls.
Long-term administration of artesunate induces reproductive toxicity in male rats
Hence the objective of this study was to isolate the protein from these extracts and to study its effects on sperm in vitro in comparison with nonoxynol-9, a known spermicide.
Spermicidal action of a protein isolated from ethanolic root extracts of Achyranthes aspera: an in vitro study
Evaluation of a low-dose nonoxynol-9 gel for the prevention of sexually transmitted diseases: a randomized clinical trial.
Microbicides & their implications in HIV prevention
She was referring to a study of a nonoxynol-9 gel (N-9) called the COL-1492 trial.
In defence of rational aids activism: how the irrationality of Act Up-Paris and others is risking the health of people with HIV or at risk of HIV infection
In December 2007, the Food and Drug Administration (FDA) issued a rule requiring over-the-counter vaginal contraceptives (gels, foams, creams) that contain nonoxynol-9 (N-9) to carry warning labels alerting the consumer that N-9 does not reduce the risk of HIV infection and could increase a woman's risk of becoming infected.
In December 2007, the Food and Drug Administration (FDA) issued a rule requiring over-the-counter vaginal contraceptives (gels, foams, creams) that contain nonoxynol-9 (N-9) to carry warning labels alerting the consumer that N-9 does not reduce the risk of HIV infection and could increase a woman's risk of becoming infected
For example, three programs promoted the use of the spermicide nonoxynol-9, but the report states that recent research has shown that nonoxynol-9 is ineffective against STDs and has the potential to increase the risk of transmission.
Abstinence-only education doesn't curb sexual activity
Nonoxynol-9, the most widely used spermicide, has come under scrutiny because its strong detergent properties--which make it lethal to sperm--irritate the lining of the genital tract of some women.
Spermicide flip side: compound may promote papillomavirus infection
While the final data on what went wrong with the Ushercell trial remained outstanding at the time of writing, researchers believe nonoxynol-9 harmed participants by causing lesions in the vagina.
Tenofovir gel--the new HIV prevention 'banker'?
Specifically, the report takes issue with the use in one curriculum of the term "dental dam" instead of "rubber dam," notes that three programs included out-dated information on the spermicide nonoxynol-9 and faults one program for citing an inaccurate condom failure rate (12% rather than 15%).
Under increased pressure, abstinence-only advocates intensify campaign to protect their funding
17) Frequent use of spermicides containing nonoxynol-9 (N-9) may increase the risk of re-infection with other strains of HIV because N-9 can disrupt the lining of the vagina, making it more vulnerable to infection.
Contraceptive options for HIV-infected women
Spermicides--as well as diaphragms and cervical caps, which are used in conjunction with spermicides--are not recommended for women living with HIV, on the basis of findings that question the safety of nonoxynol-9.
Meeting the sexual and reproductive health needs of people living with HIV

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