nonmyelinic spongiform encephalomyelopathies

nonmyelinic spongiform encephalomyelopathies

a group of diseases that includes bovine citrullinemia, scrapie, bovine spongiform encephalopathy, the internationally infamous disease known as 'mad cow disease', Creutzfeld-Jakob disease, Gerstmann-Straussler disease (the last two are diseases of humans), and neuronal vacuolar degeneration of Angora goats and focal spongiform encephalopathy of dogs; in all of these diseases spongiform vacuolation of neurons and their processes is the characteristic lesion.