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A class of radiographic contrast media that do not ionize in solution, thereby decreasing effective osmolarity and toxicity.
See also: low osmolar contrast agent.


Radiographic contrast media that do not ionize in solution, decreasing effective osmolarity and toxicity.
References in periodicals archive ?
Nonionic surfactants have several advantages over ionic types for many applications.
As a result, they have been replaced, for the most part except for gastrointestinal and urologic procedures, with nonionic second-generation water-soluble agents that are associated with fewer adverse reactions.
The following figures show the level of ADBAC exhausted as a function of the concentration of the co-formulated nonionic surfactant, polyethylene-oxide 12 (Figure 4) and small quat, tetramethyl ammonium chloride (Figure 5).
Dow Corning CE-8411 Smooth Plus Emulsion is a milky white, pourable nonionic emulsion with amine and polyether functionality and an active silicone content of about 56 percent.
For clays modified with zwitterion, nonionic and anionic surfactants (TMG, HEC, TRITON X-100, LABSA and SLES), it was seen that the liquid limit and plasticity index increased when surfactant percentage was increased.
Metrohm offers an automated titration without the disadvantages of standard two-phase procedures when analysing anionic, cationic, or nonionic surfactants using the Metrohm Titrando
Exposure of cells to etoposide/UV also resulted in formation of ladder which was not very prominent in these cells in presence of surfactant/ nonionic polymer.
"The use of IV low-osmolality nonionic iodinated contrast material for imaging of pediatric patients is quite safe," concluded Jonathan R.
A large series of the adverse effects of intravenous contrast media from Japan (Japanese Committee Report on 337 647 cases) have noted that adverse drug reactions to ionic and nonionic contrast are about 12 and 3 %, respectively; however, no cases of sialadenitis have been reported in that study (6).
There were no unusual deviations with the NP(EO)[.sub.x] surfactants, except when a large hydrophobe nonionic surfactant [e.g., [C.sub.18][H.sub.37](EO)[.sub.100]] is added.
The team found that in a nonionic solution, the molecules performed only as resistors.