The recently presented Drug-Eluting Balloon for In-Stent Restenosis (DARE) Trial at the Transcatheter Cardiovascular Therapeutics (TCT) annual conference has shown that treatment with SeQuent Please was noninferior
to XIENCE in terms of 6-month minimal lumen diameter (MLD).
Formoterol was noninferior
to placebo for the primary safety endpoint, defined as a first occurrence of respiratory-related death, COPD-related emergency department visit, or COPD-related hospitalization, with an estimated hazard ratio of 0.
The new glucose-lowering medication is found to be noninferior
, ie, similar, to placebo regarding cardiovascular safety if the upper bound of the two-sided 95% confidence interval for the estimated risk ratio is less than 1.
Rifamycin was noninferior
to ciprofloxacin on every endpoint in this trial," Robert Steffen, MD, said at the annual Digestive Disease Week[R].
FOR SELECTED PATIENTS with basal cell carcinoma, one-stop shopping--diagnosing, subtyping, and excising the lesion all in one visit--using reflectance confocal microscopy was found noninferior
to the standard approach of obtaining a punch biopsy to diagnose and subtype the lesion in one visit and performing surgical excision in a separate visit.
The research team concluded that in moderate doses, celecoxib was found to be noninferior
to ibuprofen or naproxen with respect to cardiovascular safety.
Four phase 3 randomized controlled trials (EORTC 55971, CHORUS, JCOG0602, and SCORPION) suggest that NACT is noninferior
to PCS with regard to progression-free survival and overall survival.
Immunogenicity was found to be noninferior
with 2 doses in persons aged 9 through 14 years compared with 3 doses in a group in which clinical efficacy was demonstrated (GRADE evidence type 3).
Mixing the RotaTeq and Rotarix rotavirus vaccines schedules resulted in noninferior
immunogenicity compared with using only one vaccine schedule, found a new multicenter, open-label study, said Dr.
In contrast, for patients with stage IV disease, our results confirm that NACT is noninferior
to PCS for survival, with fewer ICU admissions and rehospitalizations, which suggests that NACT may be preferable for patients with stage IV ovarian cancer," they wrote in the Journal of Clinical Oncology (2016.
In a head-to-head comparison with the existing approved anthrax vaccine in a gold-standard animal model, a single intranasal dose of NasoShield showed complete protection from inhalation anthrax and was noninferior
to multiple doses of the existing approved anthrax vaccine, while providing for a more rapid and stable immune response, according to the company.
Thus, gradual cessation did not prove to be noninferior
to abrupt cessation.