The researchers found that daily netarsudil was noninferior
to twice-daily timolol, with a mean treated IOP range from 16.3 to 17.9 mm Hg for netarsudil and 16.7 to 17.6 mm Hg for timolol (mean reductions from baseline of 3.9 to 4.7 mm Hg and 3.8 to 5.2 mm Hg, respectively).
FDA-Approved Botulinum Toxins for Aesthetic Use Agent Bacterial Units/Vial Noninferiority Production (Product Studies Strain Specific) (a) AbobotulinumtoxinA Hall NCTC 125/300/350 -- (4) 2916 IncobotulinumtoxinA Hall ATCC 50/100/200 Noninferior
to (5) 3502 onabotulinumtoxinA (6) OnabotulinumtoxinA Hall-hyper 50/100/200 -- (7) Prabotu1inumtoxin -- 100 Noninferior
to A-xvfs (8) onabotulinumtoxinA (9) (a) The potency units of each product are specific to that product and are not interchangeable with those for other products.
The primary endpoint for this study conducted exclusively in women, was previously presented, and demonstrated noninferior
maintained virologic suppression, with a low frequency of serious adverse events and no emergent resistance at Week 48.
Two years later, death from any cause and overall rates of stroke were the same for both groups, leading the researchers to determine that TAVR is noninferior
to surgery in low-risk patients.
The trial is structured to test the hypothesis that the single-session intervention will be noninferior
to the full 8 weeks of CBT, Dr.
SEATTLE -- A long-acting, injectable combination of the novel integrase inhibitor cabotegravir (CAB) and the second-generation nonnucleoside reverse transcriptase inhibitor rilpivirine (RPV) was noninferior
to dolutegravir/abacavir/lamivudine (DTG/ABC/3TC) in one phase 3 study (FLAIR) and to three-drug oral antiretroviral therapy (ART) more broadly in the companion ATLAS phase 3 study.
Left atrial appendage closure (LAAC) with the Watchman device is noninferior
to vitamin K antagonists (VKAs) and non-VKA oral anticoagulants (NOACs) for adults with nonvalvular atrial fibrillation (NVAF) and 1 additional stroke risk factor (strength of recommendation [SOR]: A, multiple meta-analyses).
The postvaccination antipertussis geometric mean concentrations were noninferior
in the Tdap group, compared with the Td group, Dr.
Over a 24-month follow-up period, knee function, as assessed by a patient questionnaire, improved in both treatment groups and slightly more in the surgery group; however, the researchers concluded that physical therapy was "noninferior
" to surgery [Journal of the American Medical Association, online Oct.
As previously reported and as shown in Figure 1, SATE estimates were either conclusively noninferior
(DSM, serious morbidity, morbidity, pneumonia, unplanned reoperation, sepsis, SSI, UTI) or inconclusively noninferior
to standard duty hour policy (death, failure-to-rescue, renal failure) (Bilimoria et al.
Although trials conducted in Europe found ulipristal to be superior to placebo and noninferior
to leuprolide acetate in controlling bleeding and reducing leiomyoma size, those initial trials were conducted in a predominantly white population.